Literature DB >> 19888522

The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids.

Timothy R Rudd1, Mark A Skidmore, Scott E Guimond, Joseph Holman, Jeremy E Turnbull, Robert M Lauder, David G Fernig, Edwin A Yates.   

Abstract

The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm. Principal component analysis of the spectra allowed their differentiation into a number of groups related to the means of their production reflecting the structural changes introduced by each process. The findings suggest that CD provides a complementary technique for the rapid analysis of heparin preparations.

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Year:  2009        PMID： 19888522     DOI： 10.1160/TH08-12-0797

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN： 0340-6245            Impact factor:   5.249


  6 in total

1.  Controlled Photochemical Depolymerization of K5 Heparosan, a Bioengineered Heparin Precursor.

Authors:  Kyohei Higashi; Mellisa Ly; Zhenyu Wang; Sayaka Masuko; Ujjwal Bhaskar; Eric Sterner; Fuming Zhang; Toshihiko Toida; Jonathan S Dordick; Robert J Linhardt
Journal:  Carbohydr Polym       Date:  2011-08-01       Impact factor: 9.381

2.  Analysis of E. coli K5 capsular polysaccharide heparosan.

Authors:  Mellisa Ly; Zhenyu Wang; Tatiana N Laremore; Fuming Zhang; Weihong Zhong; Dennis Pu; Dmitri V Zagorevski; Jonathan S Dordick; Robert J Linhardt
Journal:  Anal Bioanal Chem       Date:  2010-04-21       Impact factor: 4.142

3.  A new approach for heparin standardization: combination of scanning UV spectroscopy, nuclear magnetic resonance and principal component analysis.

Authors:  Marcelo A Lima; Timothy R Rudd; Eduardo H C de Farias; Lyvia F Ebner; Tarsis F Gesteira; Lauro M de Souza; Aline Mendes; Carolina R Córdula; João R M Martins; Debra Hoppensteadt; Jawed Fareed; Guilherme L Sassaki; Edwin A Yates; Ivarne L S Tersariol; Helena B Nader
Journal:  PLoS One       Date:  2011-01-18       Impact factor: 3.240

4.  Glycomics approaches for the bioassay and structural analysis of heparin/heparan sulphates.

Authors:  Tania M Puvirajesinghe; Jeremy E Turnbull
Journal:  Metabolites       Date:  2012-11-28

5.  Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus.

Authors:  Courtney J Mycroft-West; Anthony J Devlin; Lynsay C Cooper; Patricia Procter; Gavin J Miller; David G Fernig; Marco Guerrini; Scott E Guimond; Marcelo A Lima; Edwin A Yates; Mark Andrew Skidmore
Journal:  Neural Regen Res       Date:  2020-08       Impact factor: 5.135

6.  Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer's Disease β Secretase, BACE1.

Authors:  Courtney J Mycroft-West; Anthony J Devlin; Lynsay C Cooper; Scott E Guimond; Patricia Procter; Marco Guerrini; Gavin J Miller; David G Fernig; Edwin A Yates; Marcelo A Lima; Mark A Skidmore
Journal:  Mar Drugs       Date:  2021-04-03       Impact factor: 5.118
  6 in total

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