Literature DB >> 19887803

Why do the clients of Georgian needle exchange programmes inject buprenorphine?

David Otiashvili1, Tomas Zabransky, Irma Kirtadze, Gvantsa Piralishvili, Marina Chavchanidze, Michal Miovsky.   

Abstract

AIM: The aim of the study was to understand the prevalence and patterns of the non-medical injecting use of buprenorphine among drug injectors in Georgia.
METHOD: A self-administered questionnaire was distributed among injecting drug users enrolled in Georgian needle exchange programmes. The questions covered topics related to drug use career, patterns (frequency, history, dosage) and reasons for the use of buprenorphine.
RESULTS: Pharmaceutical buprenorphine in the form of Subutex was the most commonly injected drug in terms of lifetime (95.5%) and last-month (75%) prevalence of use. 48% of those study participants who had injected Subutex at some point reported having used it to cope with withdrawal or to give up other opioids. 90.5% of Subutex injectors used 1-2 mg as a single dose, and the mean frequency of its injection was 6 times per month. 75% of Subutex injectors had used 3 or more types of illegal drugs during the last 30 days.
CONCLUSION: While widely misused by Georgian drug injectors, Subutex is neither the principal nor the favourite drug, and it is rather used as self-treatment. The authors consider the introduction of buprenorphine maintenance treatment to be a promising effective measure to decrease its non-medical and illegal use. Copyright 2009 S. Karger AG, Basel.

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Year:  2009        PMID: 19887803     DOI: 10.1159/000253858

Source DB:  PubMed          Journal:  Eur Addict Res        ISSN: 1022-6877            Impact factor:   3.015


  15 in total

1.  Drug use and HIV risk outcomes in opioid-injecting men in the Republic of Georgia: behavioral treatment + naltrexone compared to usual care.

Authors:  David Otiashvili; Irma Kirtadze; Kevin E O'Grady; Hendrée E Jones
Journal:  Drug Alcohol Depend       Date:  2011-07-13       Impact factor: 4.492

Review 2.  HIV, Drug Injection, and Harm Reduction Trends in Eastern Europe and Central Asia: Implications for International and Domestic Policy.

Authors:  Katherine LaMonaca; Kostyantyn Dumchev; Sergii Dvoriak; Lyuba Azbel; Olga Morozova; Frederick L Altice
Journal:  Curr Psychiatry Rep       Date:  2019-06-03       Impact factor: 5.285

3.  Unsafe injection and sexual risk behavior among injecting drug users in Georgia.

Authors:  Ivdity Chikovani; Ivana Bozicevic; Ketevan Goguadze; Natia Rukhadze; George Gotsadze
Journal:  J Urban Health       Date:  2011-08       Impact factor: 3.671

Review 4.  Buprenorphine and buprenorphine/naloxone diversion, misuse, and illicit use: an international review.

Authors:  Michael A Yokell; Nickolas D Zaller; Traci C Green; Josiah D Rich
Journal:  Curr Drug Abuse Rev       Date:  2011-03

5.  Behavioral treatment + naltrexone reduces drug use and legal problems in the Republic of Georgia.

Authors:  Irma Kirtadze; David Otiashvili; Kevin E O'Grady; Hendrée E Jones
Journal:  Am J Drug Alcohol Abuse       Date:  2012-01-05       Impact factor: 3.829

6.  Intravenous buprenorphine and norbuprenorphine pharmacokinetics in humans.

Authors:  M A Huestis; E J Cone; S O Pirnay; A Umbricht; K L Preston
Journal:  Drug Alcohol Depend       Date:  2012-12-14       Impact factor: 4.492

7.  Methadone and buprenorphine-naloxone are effective in reducing illicit buprenorphine and other opioid use, and reducing HIV risk behavior--outcomes of a randomized trial.

Authors:  David Otiashvili; Gvantsa Piralishvili; Zura Sikharulidze; George Kamkamidze; Sabrina Poole; George E Woody
Journal:  Drug Alcohol Depend       Date:  2013-07-31       Impact factor: 4.492

Review 8.  Policing, massive street drug testing and poly-substance use chaos in Georgia - a policy case study.

Authors:  David Otiashvili; Mzia Tabatadze; Nino Balanchivadze; Irma Kirtadze
Journal:  Subst Abuse Treat Prev Policy       Date:  2016-01-16

9.  Female partners of opioid-injecting men in the Republic of Georgia: an initial characterization.

Authors:  Ingunn O Lund; Irma Kirtadze; David Otiashvili; Kevin E O'Grady; Hendrée E Jones
Journal:  Subst Abuse Treat Prev Policy       Date:  2012-11-16

10.  Illicit use of methadone and buprenorphine among adolescents and young adults in Sweden.

Authors:  Torkel Richert; Björn Johnson
Journal:  Harm Reduct J       Date:  2013-10-18
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