AIM: This study investigates the effect of rapid weight gain in term children, adolescents and young adults born appropriate for gestational age. METHODS: In all, 173 girls and 178 boys aged 6.1-19.9 (12.5 +/- 3.1)years participated. Rapid weight gain (group 1) was defined as a change in weight-SDS (standard deviation score) from birth till two years >0.67, 'no change' as > or =-0.67 and < or =0.67 (group 2) vs 'slow weight gain' as <-0.67 (group 3). BMI-SDS, waist circumference (WC) z-score, fat mass (FM)/fat free mass (FFM; Air-Displacement-Plethysmography), resting energy expenditure (REE; ventilated hood system), cardio-metabolic risk factors, serum leptin and adiponectin were assessed. >90th age-/sex-specific BMI-percentile was defined as overweight. Parental BMI, socio-economic status and lifestyle were assessed as confounders. RESULTS: A total of 22.8% gained weight rapidly, and 15.7% was overweight. Group 1 compared with group 2 and 3 subjects was taller, heavier and had a higher prevalence of overweight (girls/boys: 26.2%/28.9% vs 11.6%/19.0% vs 2.8%/5.0%; p < 0.01/p < 0.05). Concomitantly, a higher WC, %FM and FFM were observed. Rapid weight gain was positively associated with REE (adjusted for FFM) in boys (r = 0.26; p < 0.01), but not with cardio-metabolic risk factors. CONCLUSION: Rapid weight gain was related to increases in height, weight, a higher prevalence of overweight and central fat distribution. In addition, rapid weight gain was related to a higher REE in boys, but not to cardio-metabolic risk factors.
AIM: This study investigates the effect of rapid weight gain in term children, adolescents and young adults born appropriate for gestational age. METHODS: In all, 173 girls and 178 boys aged 6.1-19.9 (12.5 +/- 3.1)years participated. Rapid weight gain (group 1) was defined as a change in weight-SDS (standard deviation score) from birth till two years >0.67, 'no change' as > or =-0.67 and < or =0.67 (group 2) vs 'slow weight gain' as <-0.67 (group 3). BMI-SDS, waist circumference (WC) z-score, fat mass (FM)/fat free mass (FFM; Air-Displacement-Plethysmography), resting energy expenditure (REE; ventilated hood system), cardio-metabolic risk factors, serum leptin and adiponectin were assessed. >90th age-/sex-specific BMI-percentile was defined as overweight. Parental BMI, socio-economic status and lifestyle were assessed as confounders. RESULTS: A total of 22.8% gained weight rapidly, and 15.7% was overweight. Group 1 compared with group 2 and 3 subjects was taller, heavier and had a higher prevalence of overweight (girls/boys: 26.2%/28.9% vs 11.6%/19.0% vs 2.8%/5.0%; p < 0.01/p < 0.05). Concomitantly, a higher WC, %FM and FFM were observed. Rapid weight gain was positively associated with REE (adjusted for FFM) in boys (r = 0.26; p < 0.01), but not with cardio-metabolic risk factors. CONCLUSION: Rapid weight gain was related to increases in height, weight, a higher prevalence of overweight and central fat distribution. In addition, rapid weight gain was related to a higher REE in boys, but not to cardio-metabolic risk factors.
Authors: Marie S Thearle; Susanne B Votruba; Paolo Piaggi; Yunhua L Muller; Robert L Hanson; Leslie J Baier; William Knowler; Jonathan Krakoff Journal: Obesity (Silver Spring) Date: 2015-09 Impact factor: 5.002
Authors: Annemieke M V Evelein; Frank L J Visseren; Cornelis K van der Ent; Diederick E Grobbee; Cuno S P M Uiterwaal Journal: Int J Pediatr Date: 2012-05-09
Authors: Esther M Leerkes; Cheryl Buehler; Susan D Calkins; Lenka H Shriver; Laurie Wideman Journal: BMC Public Health Date: 2020-12-14 Impact factor: 3.295