Literature DB >> 19886142

Elevated blood alcohol level may be protective of trauma patient mortality.

Arezou Yaghoubian1, Amy Kaji, Brant Putnam, Nicholas De Virgilio, Christian De Virgilio.   

Abstract

To determine whether a positive blood alcohol level (BAL) affects morbidity and mortality at a Level I trauma center, a retrospective review of trauma patients 18 years of age and older was performed. There were 7985 trauma patients and 8 per cent (645) had a positive BAL. BAL(+) patients had lower Injury Severity Score (ISS) (8 vs 11, P < 0.01), lower rate of penetrating injury (9 vs 25%, P < 0.01), and were older (38 vs 32 years, P = 0.01). Overall there were 559 deaths (7%); (1% mortality in BAL(+) patients and 7% in BAL(-) patients; P < 0.0001). There were 352 (4.4%) complications with similar rates among BAL(-) and (+) patients. On univariate analysis, a positive BAL was inversely associated with death (OR, 0.17) as was blunt trauma (OR, 0.29), whereas older age (OR 1.009) and increased ISS (OR 1.13) were associated with death. On multivariable analysis, after adjusting for age, ISS, and mechanism of injury, a positive BAL remained protective against death (OR 0.35) as did blunt trauma (OR 0.2). Age (OR 1.04) and increased ISS (OR 1.19) were associated with mortality. In conclusion, a positive BAL was associated with a decreased mortality risk in trauma patients, which persisted after adjusting for multiple confounding variables.

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Year:  2009        PMID: 19886142

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  11 in total

1.  Alcohol exposure, injury, and death in trauma patients.

Authors:  Majid Afshar; Giora Netzer; Sarah Murthi; Gordon S Smith
Journal:  J Trauma Acute Care Surg       Date:  2015-10       Impact factor: 3.313

2.  Risk of pneumonia in central nervous system injury with alcohol intake: a meta-analysis.

Authors:  Chunming Sun; Liang Shen; Xuetao Li; Chuanjin Liu; Youxin Zhou
Journal:  Int J Clin Exp Med       Date:  2015-09-15

3.  Alcohol use at time of injury and survival following traumatic brain injury: results from the National Trauma Data Bank.

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4.  Alcohol use by urban bicyclists is associated with more severe injury, greater hospital resource use, and higher mortality.

Authors:  Monica Sethi; Jessica H Heyer; Stephen Wall; Charles DiMaggio; Matthew Shinseki; Dekeya Slaughter; Spiros G Frangos
Journal:  Alcohol       Date:  2016-04-09       Impact factor: 2.405

5.  Alcohol exposure and outcomes in trauma patients.

Authors:  P Hadjizacharia; T O'Keeffe; D S Plurad; D J Green; C V R Brown; L S Chan; D Demetriades; P Rhee
Journal:  Eur J Trauma Emerg Surg       Date:  2010-07-22       Impact factor: 3.693

6.  Circulating Extracellular Vesicles and Their miR "Barcode" Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients.

Authors:  Akiko Eguchi; Niklas Franz; Yoshinao Kobayashi; Motoh Iwasa; Nils Wagner; Frank Hildebrand; Yoshiyuki Takei; Ingo Marzi; Borna Relja
Journal:  Front Med (Lausanne)       Date:  2019-02-25

7.  Comparison of injury pattern and clinical outcomes between young adults and elderly patients with alcohol-related injury in South Korea 2011-2016.

Authors:  Jae Hee Lee; Duk Hee Lee
Journal:  PeerJ       Date:  2019-09-27       Impact factor: 2.984

8.  Traumatic Brain Injury: A Forensic Approach: A Literature Review.

Authors:  Giuseppe Bertozzi; Francesca Maglietta; Francesco Sessa; Edmondo Scoto; Luigi Cipolloni; Giulio Di Mizio; Monica Salerno; Cristoforo Pomara
Journal:  Curr Neuropharmacol       Date:  2020       Impact factor: 7.363

9.  A Ten year review of alcohol use and major trauma in a Canadian province: still a major problem.

Authors:  Jessica McKee; Sandy L Widder; J Damian Paton-Gay; Andrew W Kirkpatrick; Paul Engels
Journal:  J Trauma Manag Outcomes       Date:  2016-01-21

10.  The effect of ethyl alcohol on the severity of injuries in fatal pedestrian victims of traffic crashes.

Authors:  Dorota Lasota; Mariusz Goniewicz; Dariusz Kosson; Andrzej Ochal; Paweł Krajewski; Sylwia Tarka; Krzysztof Goniewicz; Dagmara Mirowska-Guzel
Journal:  PLoS One       Date:  2019-09-10       Impact factor: 3.240

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