OBJECTIVE: To identify potential risk factors associated with a sudden increase in gastroschisis cases in northern Nevada. DESIGN: Case-control study. SETTING: Medical centers and a pregnancy care center in Reno, Nevada. PARTICIPANTS: Participants (n = 14) were women who gave birth to infants with gastroschisis at either of the 2 medical centers in Reno, Nevada, from April 5, 2007, through April 4, 2008. Controls (n = 57) were selected from the same pregnancy center providing perinatal care to the cases and were matched 4:1 to the case mothers by maternal date of birth within 1 year. MAIN EXPOSURES: Environmental exposures and illnesses during pregnancy. OUTCOME MEASURES: Association of gastroschisis with illnesses, medications, or environmental exposures. RESULTS: Gastroschisis was associated with the use of methamphetamine (odds ratio [OR], 7.15; 95% confidence interval [CI], 1.35-37.99) or any vasoconstrictive recreational drug (methamphetamine, amphetamine, cocaine, ecstasy) (OR, 4.46; 95% CI, 1.21-16.44) before pregnancy. When we limited self-reported illnesses to those occurring during the first trimester of pregnancy, chest colds (OR, 16.77; 95% CI, 1.88-150.27) and sore throats (OR, 12.72; 95% CI, 1.32-122.52) were associated with gastroschisis. CONCLUSIONS: These findings add strength to the hypothesis that use of methamphetamine and related drugs is a risk factor for gastroschisis and raise questions about the risks associated with infections.
OBJECTIVE: To identify potential risk factors associated with a sudden increase in gastroschisis cases in northern Nevada. DESIGN: Case-control study. SETTING: Medical centers and a pregnancy care center in Reno, Nevada. PARTICIPANTS: Participants (n = 14) were women who gave birth to infants with gastroschisis at either of the 2 medical centers in Reno, Nevada, from April 5, 2007, through April 4, 2008. Controls (n = 57) were selected from the same pregnancy center providing perinatal care to the cases and were matched 4:1 to the case mothers by maternal date of birth within 1 year. MAIN EXPOSURES: Environmental exposures and illnesses during pregnancy. OUTCOME MEASURES: Association of gastroschisis with illnesses, medications, or environmental exposures. RESULTS: Gastroschisis was associated with the use of methamphetamine (odds ratio [OR], 7.15; 95% confidence interval [CI], 1.35-37.99) or any vasoconstrictive recreational drug (methamphetamine, amphetamine, cocaine, ecstasy) (OR, 4.46; 95% CI, 1.21-16.44) before pregnancy. When we limited self-reported illnesses to those occurring during the first trimester of pregnancy, chest colds (OR, 16.77; 95% CI, 1.88-150.27) and sore throats (OR, 12.72; 95% CI, 1.32-122.52) were associated with gastroschisis. CONCLUSIONS: These findings add strength to the hypothesis that use of methamphetamine and related drugs is a risk factor for gastroschisis and raise questions about the risks associated with infections.
Authors: Kayla N Anderson; Annelise C Dutton; Cheryl S Broussard; Sherry L Farr; Jennifer N Lind; Susanna N Visser; Elizabeth C Ailes; Stuart K Shapira; Jennita Reefhuis; Sarah C Tinker Journal: J Atten Disord Date: 2018-03-09 Impact factor: 3.256
Authors: Mahsa M Yazdy; Martha M Werler; Marcia L Feldkamp; Gary M Shaw; Bridget S Mosley; Veronica M Vieira Journal: Birth Defects Res A Clin Mol Teratol Date: 2015-04-06
Authors: Martha M Werler; Samantha E Parker; Klaus Hedman; Mika Gissler; Annukka Ritvanen; Heljä-Marja Surcel Journal: Am J Epidemiol Date: 2016-11-17 Impact factor: 4.897
Authors: Mahsa M Yazdy; Martha M Werler; Marlene Anderka; Peter H Langlois; Veronica M Vieira Journal: Ann Epidemiol Date: 2014-10-13 Impact factor: 3.797
Authors: Russell S Kirby; Jennifer Marshall; Jean Paul Tanner; Jason L Salemi; Marcia L Feldkamp; Lisa Marengo; Robert E Meyer; Charlotte M Druschel; Russel Rickard; James E Kucik Journal: Obstet Gynecol Date: 2013-08 Impact factor: 7.623