Literature DB >> 1988413

A case report of cimetidine-induced clozapine toxicity.

S Szymanski1, J A Lieberman, D Picou, S Masiar, T Cooper.   

Abstract

Cimetidine may decrease concomitant medication clearance by inhibiting the oxidative system of cytochrome P-450. The authors report increased serum clozapine levels and adverse side effects during clozapine and cimetidine treatment but not during clozapine and ranitidine treatment in a patient with chronic paranoid schizophrenia.

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Year:  1991        PMID： 1988413

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN： 0160-6689            Impact factor:   4.384


  12 in total

Review 1.  Clinical profile of clozapine: adverse reactions and agranulocytosis.

Authors:  J A Lieberman; A Z Safferman
Journal:  Psychiatr Q       Date:  1992

2.  A therapeutic interaction between cimetidine and clozapine: case study and review of the literature.

Authors:  Magdalena Watras; David Taylor
Journal:  Ther Adv Psychopharmacol       Date:  2013-10

Review 3.  Clinically significant drug interactions with atypical antipsychotics.

Authors:  William Klugh Kennedy; Michael W Jann; Eric C Kutscher
Journal:  CNS Drugs       Date:  2013-12       Impact factor: 5.749

Review 4.  Will routine therapeutic drug monitoring have a place in clozapine therapy?

Authors:  D J Freeman; L K Oyewumi
Journal:  Clin Pharmacokinet       Date:  1997-02       Impact factor: 6.447

5.  Antiparkinsonian Agents : Clinically Significant Drug Interactions and Adverse Effects, and Their Management.

Authors:  A Dalvi; B Ford
Journal:  CNS Drugs       Date:  1998-04       Impact factor: 5.749

Review 6.  Clozapine plasma level monitoring: current status.

Authors:  T B Cooper
Journal:  Psychiatr Q       Date:  1996

Review 7.  Pharmacokinetics and pharmacodynamics of clozapine.

Authors:  M W Jann; S R Grimsley; E C Gray; W H Chang
Journal:  Clin Pharmacokinet       Date:  1993-02       Impact factor: 6.447

Review 8.  A comparative overview of the adverse effects of antiulcer drugs.

Authors:  D W Piper
Journal:  Drug Saf       Date:  1995-02       Impact factor: 5.606

Review 9.  Therapeutic drug monitoring of clozapine treatment. Therapeutic threshold value for serum clozapine concentrations.

Authors:  O V Olesen
Journal:  Clin Pharmacokinet       Date:  1998-06       Impact factor: 6.447

10.  A Kinetic Model for Simultaneous Fit of Clozapine and Norclozapine Concentrations in Chronic Schizophrenic Patients during Long-Term Treatment.

Authors:  C Guitton; J M Kinowski; R Gomeni; F Bressolle
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859
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