Literature DB >> 19883082

Evolution of efficient strategies for enone-alkyne and enal-alkyne reductive couplings.

Wei Li1, Ananda Herath, John Montgomery.   

Abstract

Strategies for the reductive coupling of enones or enals with alkynes have been developed. The reducing agents employed include organozincs, organoboranes, organosilanes, and methanol. The latter of these strategies is simple, cost-effective, and tolerant of many functional groups. Isotopic labeling strategies have provided supporting evidence for the mechanistic proposals.

Entities:  

Year:  2009        PMID: 19883082     DOI: 10.1021/ja9083607

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  6 in total

1.  Nickel-catalyzed reductive conjugate addition to enones via allylnickel intermediates.

Authors:  Ruja Shrestha; Stephanie C M Dorn; Daniel J Weix
Journal:  J Am Chem Soc       Date:  2013-01-08       Impact factor: 15.419

2.  Ni(II) salts and 2-propanol effect catalytic reductive coupling of epoxides and alkynes.

Authors:  Matthew G Beaver; Timothy F Jamison
Journal:  Org Lett       Date:  2011-06-30       Impact factor: 6.005

3.  Simplifying nickel(0) catalysis: an air-stable nickel precatalyst for the internally selective benzylation of terminal alkenes.

Authors:  Eric A Standley; Timothy F Jamison
Journal:  J Am Chem Soc       Date:  2013-01-14       Impact factor: 15.419

4.  Nickel-Catalyzed Reductive Conjugate Addition of Primary Alkyl Bromides to Enones To Form Silyl Enol Ethers.

Authors:  Kierra M M Huihui; Ruja Shrestha; Daniel J Weix
Journal:  Org Lett       Date:  2017-01-05       Impact factor: 6.005

5.  Divergent ring-opening coupling between cyclopropanols and alkynes under cobalt catalysis.

Authors:  Junfeng Yang; Yixiao Shen; Yang Jie Lim; Naohiko Yoshikai
Journal:  Chem Sci       Date:  2018-07-16       Impact factor: 9.825

6.  Ni-catalyzed regio- and stereo-defined intermolecular cross-electrophile dialkylation of alkynes without directing group.

Authors:  Yi-Zhou Zhan; Nan Xiao; Wei Shu
Journal:  Nat Commun       Date:  2021-02-10       Impact factor: 14.919

  6 in total

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