PURPOSE: To present an infant with bilateral ocular and skin involvement by juvenile xanthogranuloma and the results of treatment with vinblastine. METHODS: Analysis of the clinical and histopathologic data and the results of the treatment. RESULTS: After 14 months' evolution with no response to other treatments, the lesions responded to a course of vinblastine (6 mg/m2/weekly, corrected for weight), which was followed by a maintenance treatment for 52 weeks. CONCLUSIONS: The treatment protocol used in the present case may prove useful for similar patients. We found no other report describing these results.
PURPOSE: To present an infant with bilateral ocular and skin involvement by juvenile xanthogranuloma and the results of treatment with vinblastine. METHODS: Analysis of the clinical and histopathologic data and the results of the treatment. RESULTS: After 14 months' evolution with no response to other treatments, the lesions responded to a course of vinblastine (6 mg/m2/weekly, corrected for weight), which was followed by a maintenance treatment for 52 weeks. CONCLUSIONS: The treatment protocol used in the present case may prove useful for similar patients. We found no other report describing these results.
Authors: R Muralidhar; Ashish Jain; P Vijayalakshmi; G Suparna; R Santhi; Shashikanth Shetty Journal: Indian J Ophthalmol Date: 2013-11 Impact factor: 1.848