PURPOSE: To identify risk factors for the development of culture-positive endophthalmitis after repair of open globe injuries. METHODS: We retrospectively reviewed the medical records of 629 consecutive patients with open globe injuries admitted to King Abdulaziz University Hospital between May 1996 and January 2008. RESULTS: Endophthalmitis developed in 12 (1.9%) patients. The following factors were significantly associated with endophthalmitis by univariate analysis: delayed presentation (>24 hours) (p=0.008), rural address (p=0.013), and dirty wound (p=0.012). Logistic regression analysis identified dirty wound to be associated with the development of endophthalmitis (odds ratio = 11.6; 95% confidence interval [CI] = 2.67-50.6). On logistic regression analysis, presence of retained intraocular foreign body (IOFB) in association with rural address (odds ratio = 11.0; 95% CI = 1.44-83.3) or dirty wound (odds ratio = 9.2; 95% CI = 1.22-69.1) was associated with development of endophthalmitis. Endophthalmitis was a significant negative predictor for final good visual outcome (p=0.00261) and was significantly associated with hypotony (p=0.033). CONCLUSIONS: Delayed presentation, rural address, and dirty wound were associated with development of endophthalmitis. Retained IOFB in association with rural address or dirty wound was associated with a particularly high risk of endophthalmitis.
PURPOSE: To identify risk factors for the development of culture-positive endophthalmitis after repair of open globe injuries. METHODS: We retrospectively reviewed the medical records of 629 consecutive patients with open globe injuries admitted to King Abdulaziz University Hospital between May 1996 and January 2008. RESULTS:Endophthalmitis developed in 12 (1.9%) patients. The following factors were significantly associated with endophthalmitis by univariate analysis: delayed presentation (>24 hours) (p=0.008), rural address (p=0.013), and dirty wound (p=0.012). Logistic regression analysis identified dirty wound to be associated with the development of endophthalmitis (odds ratio = 11.6; 95% confidence interval [CI] = 2.67-50.6). On logistic regression analysis, presence of retained intraocular foreign body (IOFB) in association with rural address (odds ratio = 11.0; 95% CI = 1.44-83.3) or dirty wound (odds ratio = 9.2; 95% CI = 1.22-69.1) was associated with development of endophthalmitis. Endophthalmitis was a significant negative predictor for final good visual outcome (p=0.00261) and was significantly associated with hypotony (p=0.033). CONCLUSIONS: Delayed presentation, rural address, and dirty wound were associated with development of endophthalmitis. Retained IOFB in association with rural address or dirty wound was associated with a particularly high risk of endophthalmitis.
Authors: Sonia Bianchini; Chiara Morini; Laura Nicoletti; Sara Monaco; Erika Rigotti; Caterina Caminiti; Giorgio Conti; Maia De Luca; Daniele Donà; Giuseppe Maglietta; Laura Lancella; Andrea Lo Vecchio; Giorgio Marchini; Carlo Pietrasanta; Nicola Principi; Alessandro Simonini; Elisabetta Venturini; Rosa Longo; Elena Gusson; Domenico Boccuzzi; Luca Vigo; Fabio Mosca; Annamaria Staiano; Susanna Esposito Journal: Antibiotics (Basel) Date: 2022-04-22
Authors: Robert Rejdak; Tomasz Choragiewicz; Agnieszka Kalinowska; Michael J Koss; Piotr Ksiazek; Joanna Moneta-Wielgos; Ryszard Maciejewski; Anselm G Jünemann; Katarzyna Nowomiejska Journal: BMC Infect Dis Date: 2016-09-20 Impact factor: 3.090