Literature DB >> 19880916

Attitudes of patients and mental health staff to antipsychotic long-acting injections: systematic review.

Linda Waddell1, Mark Taylor.   

Abstract

BACKGROUND: The attitudes of staff and patients have been demonstrated to influence the acceptance of long-acting injections (LAIs) or depot antipsychotics. AIMS: To examine the attitudes of patients and staff to LAIs.
METHOD: A systematic review was carried out. Studies included contained quantitative data for attitudes of patients or staff to LAIs.
RESULTS: Twelve studies published subsequent to the systematic review reported in 2001 were identified. Five studies conveyed an overall positive attitude. The most positive attitudes among patients were seen in those already prescribed an LAI. Positive attitudes of staff correlated closely with the extent of their knowledge of LAIs.
CONCLUSIONS: Long-acting injections continue to have an image problem, arguably perpetuated by manufacturers of oral second-generation antipsychotic drugs, and exacerbated by the predominant use of these medications as a ;last resort' often for the most stigmatized individuals. The introduction of better-tolerated LAIs and better education of both staff and patients may encourage individuals to re-examine their attitudes.

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Year:  2009        PMID: 19880916     DOI: 10.1192/bjp.195.52.s43

Source DB:  PubMed          Journal:  Br J Psychiatry Suppl        ISSN: 0960-5371


  38 in total

1.  A qualitative study of the attitudes of patients in an early intervention service towards antipsychotic long-acting injections.

Authors:  Amlan K Das; Abid Malik; Peter M Haddad
Journal:  Ther Adv Psychopharmacol       Date:  2014-10

2.  Cross-sectional comparison of first-generation antipsychotic long-acting injections vs risperidone long-acting injection: patient-rated attitudes, satisfaction and tolerability.

Authors:  Sourabh Moti Singh; Peter M Haddad; Nusrat Husain; Eamonn Heaney; Barbara Tomenson; Imran B Chaudhry
Journal:  Ther Adv Psychopharmacol       Date:  2016-03-10

Review 3.  The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal.

Authors:  Sofia Brissos; Miguel Ruiz Veguilla; David Taylor; Vicent Balanzá-Martinez
Journal:  Ther Adv Psychopharmacol       Date:  2014-10

4.  Proposing the Use of Partial AUC as an Adjunctive Measure in Establishing Bioequivalence Between Deltoid and Gluteal Administration of Long-Acting Injectable Antipsychotics.

Authors:  Lik Hang N Lee; Charles Choi; Pavel Gershkovich; Alasdair M Barr; William G Honer; Ric M Procyshyn
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2016-12       Impact factor: 2.441

5.  A stitch in time: 3-monthly long-acting injectable paliperidone palmitate in schizophrenia.

Authors:  Mark Taylor; Hannah Chu-Han Huang
Journal:  Ther Adv Psychopharmacol       Date:  2017-07-31

Review 6.  Olanzapine long-acting injection: a review of its use in the treatment of schizophrenia.

Authors:  James E Frampton
Journal:  Drugs       Date:  2010-12-03       Impact factor: 9.546

7.  Long-acting injectable vs oral antipsychotics for relapse prevention in schizophrenia: a meta-analysis of randomized trials.

Authors:  Taishiro Kishimoto; Alfred Robenzadeh; Claudia Leucht; Stefan Leucht; Koichiro Watanabe; Masaru Mimura; Michael Borenstein; John M Kane; Christoph U Correll
Journal:  Schizophr Bull       Date:  2012-12-17       Impact factor: 9.306

8.  Indications for and use of long-acting injectable antipsychotics: consideration from an inpatient setting.

Authors:  Taishiro Kishimoto; Sohag Sanghani; Mark J Russ; Akeem N Marsh; Joshua Morris; Suparna Basu; Majnu John; John M Kane
Journal:  Int Clin Psychopharmacol       Date:  2017-05       Impact factor: 1.659

9.  The knowledge and attitudes of psychiatrists towards antipsychotic long-acting injections in Nigeria.

Authors:  Bawo O James; Joyce O Omoaregba; Kingsley M Okonoda; Edebi U Otefe; Maxine X Patel
Journal:  Ther Adv Psychopharmacol       Date:  2012-10

10.  Patients' and clinicians' attitude towards long-acting depot antipsychotics in subjects with a first episode of psychosis.

Authors:  Matthias Kirschner; Anastasia Theodoridou; Paolo Fusar-Poli; Stefan Kaiser; Matthias Jäger
Journal:  Ther Adv Psychopharmacol       Date:  2013-04
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