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Literature DB >> 19880825

Unintended effects of cranial irradiation on cognitive function.

Abstract

This review summarizes some of the topics discussed at the 28th Annual Symposium of the Society of Toxicologic Pathology. The symposium was held in Washington, DC, in 2009 and dealt with unintended adverse events associated with cranial irradiation as part of cancer therapy. We will discuss the importance of considering genetic susceptibility and sex differences in susceptibility to develop these adverse events. Further, we will discuss potential mechanisms contributing to these events, including alterations in neurogenesis and increased oxidative stress following irradiation and potential alterations in synaptic and dendritic markers.

Entities: Disease

Mesh：

Substances：
Antineoplastic Agents

Year: 2009 PMID： 19880825 DOI： 10.1177/0192623309352003

Source DB: PubMed Journal: Toxicol Pathol ISSN： 0192-6233 Impact factor: 1.902

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Cited

14 in total

1. Apolipoprotein e genotype-dependent paradoxical short-term effects of (56)fe irradiation on the brain.

Authors: Gwendolen E Haley; Laura Villasana; Catherine Dayger; Matthew J Davis; Jacob Raber
Journal: Int J Radiat Oncol Biol Phys Date: 2012-03-06 Impact factor: 7.038

2. Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction.

Authors: Munjal M Acharya; Lori-Ann Christie; Mary L Lan; Erich Giedzinski; John R Fike; Susanna Rosi; Charles L Limoli
Journal: Cancer Res Date: 2011-07-14 Impact factor: 12.701

3. Dentate gyrus neurogenesis ablation via cranial irradiation enhances morphine self-administration and locomotor sensitization.

Authors: Sarah E Bulin; Matthew L Mendoza; Devon R Richardson; Kwang H Song; Timothy D Solberg; Sanghee Yun; Amelia J Eisch
Journal: Addict Biol Date: 2017-06-19 Impact factor: 4.280

4. Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation.

Authors: Sarah J E Wong-Goodrich; Madeline L Pfau; Catherine T Flores; Jennifer A Fraser; Christina L Williams; Lee W Jones
Journal: Cancer Res Date: 2010-09-30 Impact factor: 12.701

5. Comparing the functional consequences of human stem cell transplantation in the irradiated rat brain.

Authors: Munjal M Acharya; Lori-Ann Christie; Mary L Lan; Charles L Limoli
Journal: Cell Transplant Date: 2012-04-26 Impact factor: 4.064

6. Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2).

Authors: Antiño R Allen; Kirsten Eilertson; Sourabh Sharma; Danielle Schneider; Jennifer Baure; Barrett Allen; Susanna Rosi; Jacob Raber; John R Fike
Journal: Radiat Res Date: 2013-06-17 Impact factor: 2.841

Unintended effects of cranial irradiation on cognitive function.

1. Apolipoprotein e genotype-dependent paradoxical short-term effects of (56)fe irradiation on the brain.

2. Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction.

3. Dentate gyrus neurogenesis ablation via cranial irradiation enhances morphine self-administration and locomotor sensitization.

4. Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation.

5. Comparing the functional consequences of human stem cell transplantation in the irradiated rat brain.

6. Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2).

7. Effect of the Maximum Dose on White Matter Fiber Bundles Using Longitudinal Diffusion Tensor Imaging.

8. Radio-neuroprotective effect of L-alpha-glycerylphosphorylcholine (GPC) in an experimental rat model.

9. Cranial irradiation alters dendritic spine density and morphology in the hippocampus.

Review 10. Does ionizing radiation influence Alzheimer's disease risk?