Literature DB >> 19880710

Who should consent for research in adult intensive care? Preferences of patients and their relatives: a pilot study.

C Chenaud1, P Merlani, M Verdon, B Ricou.   

Abstract

INTRODUCTION: Research in intensive care is necessary for the continuing advancement of patient care. In research, informed consent is considered essential for patient protection. In intensive care, the modalities of informed consent are currently being debated by both lawyers and the medical community. The preferences of patients and their relatives regarding informed consent for research in intensive care have never been assessed. The aim of this study was to investigate these preferences.
METHODS: A pilot study conducted via a questionnaire mailed to patients and relatives who had experienced intensive care.
RESULTS: 52/400 patient-relative pairs completed the questionnaire fully. If the patient was imagined to be conscious, 75% of patients and 77% of relatives believed the patient should be the person who should consent. If the patient was imagined to be unconscious, 72% of patients and 67% of relatives thought that a relative should be asked to consent. The majority of responders thought that at least two persons should consent. Their answers were concordant in 61-80% of cases, depending on the question. Patients (25%) and relatives (30%) did not feel free in their decision to participate in a study. The majority of patients and relatives wanted to consent by writing, indifferently with or without a witness.
CONCLUSION: Patients are willing to decide on their own participation in a study. If they lose their capacity to decide for themselves, in the great majority of cases, they would agree to delegate the decision to a relative.

Entities:  

Mesh:

Year:  2009        PMID: 19880710     DOI: 10.1136/jme.2008.028068

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  10 in total

1.  Considering the vulnerabilities of surrogate decision-makers when obtaining consent for critical care research.

Authors:  Kali A Barrett; Damon C Scales
Journal:  Intensive Care Med       Date:  2011-11-26       Impact factor: 17.440

2.  Surrogate decision makers' attitudes towards research decision making for critically ill patients.

Authors:  Kali A Barrett; Niall D Ferguson; Valerie Athaide; Deborah J Cook; Jan O Friedrich; Ellen McDonald; Ruxandra Pinto; Orla M Smith; James Stevenson; Damon C Scales
Journal:  Intensive Care Med       Date:  2012-07-24       Impact factor: 17.440

3.  Real-time perspectives of surrogate decision-makers regarding critical illness research: findings of focus group participants.

Authors:  Ellen Iverson; Aaron Celious; Carie R Kennedy; Erica Shehane; Alexander Eastman; Victoria Warren; Dragana Bolcic-Jankovic; Brian Clarridge; Bradley D Freeman
Journal:  Chest       Date:  2012-12       Impact factor: 9.410

4.  ICU research: the impact of invasiveness on informed consent.

Authors:  Fabienne Gigon; Paolo Merlani; Catherine Chenaud; Bara Ricou
Journal:  Intensive Care Med       Date:  2013-04-24       Impact factor: 17.440

5.  Attitudes to drug trials among relatives of unconscious intensive care patients.

Authors:  Anders Perner; Michael Ibsen; Jan Bonde
Journal:  BMC Anesthesiol       Date:  2010-05-26       Impact factor: 2.217

6.  Deferred consent in a minimal-risk study involving critically ill subarachnoid hemorrhage patients.

Authors:  Jane Topolovec-Vranic; Marlene Santos; Andrew J Baker; Orla M Smith; Karen E A Burns
Journal:  Can Respir J       Date:  2014-06-10       Impact factor: 2.409

7.  Using data to improve surrogate consent for clinical research with incapacitated adults.

Authors:  Emily Abdoler; David Wendler
Journal:  J Empir Res Hum Res Ethics       Date:  2012-04       Impact factor: 1.742

8.  Recall of clinical trial participation and attrition rates in survivors of acute respiratory distress syndrome.

Authors:  Erin F Carlton; Erin Ice; Ryan P Barbaro; Lee Kampuis; Marc Moss; Derek C Angus; Valerie M Banner-Goodspeed; Adit A Ginde; Michelle N Gong; Colin K Grissom; Peter C Hou; David T Huang; Catherine Terri Lee Hough; Daniel S Talmor; B Taylor Thompson; Donald M Yealy; Mick P Couper; Theodore J Iwashyna
Journal:  J Crit Care       Date:  2021-04-17       Impact factor: 4.298

Review 9.  Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness.

Authors:  Nina H Gobat; Micaela Gal; Nick A Francis; Kerenza Hood; Angela Watkins; Jill Turner; Ronald Moore; Steve A R Webb; Christopher C Butler; Alistair Nichol
Journal:  Trials       Date:  2015-12-29       Impact factor: 2.279

10.  Advances and challenges in conducting ethical trials involving populations lacking capacity to consent: A decade in review.

Authors:  Victoria Shepherd
Journal:  Contemp Clin Trials       Date:  2020-06-08       Impact factor: 2.226

  10 in total

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