Lei Yan1, Yongjie Tian, Yibing Fu, Xingbo Zhao. 1. Department of Obstetrics and Gynecology, Provincial Hospital affiliated to Shandong University, Jinan, People's Republic of China.
Abstract
OBJECTIVE: To report a case of successful pregnancy after treatment for endometrial stromal sarcoma. DESIGN: Case report. SETTING: Gynecology department at a provincial hospital affiliated with a university. PATIENT(S): A 25-year-old woman (gravida 0, para 0) with a misdiagnosis of myoma who received a pathologic diagnosis of endometrial stromal sarcoma after the first surgery. INTERVENTION(S): Second fertility-preserving surgery and chemotherapy. MAIN OUTCOME MEASURE(S): Successful pregnancy and follow-up visit. RESULT(S): After the conservative treatment, the patient entered complete remission. She conceived naturally and delivered at 39 weeks' gestation by caesarean section approximately 40 months after the surgery. CONCLUSION(S): Endometrial stromal sarcoma is a rare uterine tumor with a poor prognosis. This case shows that successful pregnancy is possible after effective conservative treatment by local surgical resection and adjunct chemotherapy. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
OBJECTIVE: To report a case of successful pregnancy after treatment for endometrial stromal sarcoma. DESIGN: Case report. SETTING: Gynecology department at a provincial hospital affiliated with a university. PATIENT(S): A 25-year-old woman (gravida 0, para 0) with a misdiagnosis of myoma who received a pathologic diagnosis of endometrial stromal sarcoma after the first surgery. INTERVENTION(S): Second fertility-preserving surgery and chemotherapy. MAIN OUTCOME MEASURE(S): Successful pregnancy and follow-up visit. RESULT(S): After the conservative treatment, the patient entered complete remission. She conceived naturally and delivered at 39 weeks' gestation by caesarean section approximately 40 months after the surgery. CONCLUSION(S): Endometrial stromal sarcoma is a rare uterine tumor with a poor prognosis. This case shows that successful pregnancy is possible after effective conservative treatment by local surgical resection and adjunct chemotherapy. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Authors: Valentina Ghirardi; Nicolò Bizzarri; Francesco Guida; Carmine Vascone; Barbara Costantini; Giovanni Scambia; Anna Fagotti Journal: Oncotarget Date: 2019-04-02