Literature DB >> 19880030

Otoneurological management of petrous apex cholesterol granuloma.

Mario Sanna1, Francesco Dispenza, Navneet Mathur, Alessandro De Stefano, Giuseppe De Donato.   

Abstract

OBJECTIVE: The aim of the study is to review the management of petrous apex cholesterol granuloma. The surgical approaches for drainage or total removal and the wait and see policy were analyzed, and outcomes were evaluated.
METHODS: Retrospective charts of 27 patients managed for petrous apex cholesterol granuloma with a minimum follow-up of 12 months were analyzed in a quartenary skull base center. Presenting symptoms and signs were recorded, and radiologic imaging was evaluated. Management options included wait and see policy and surgery by several approaches.
RESULTS: The mean age of patients affected by the lesion was 38.8 years. The mean follow-up was 56.7 months. Patients complained of hearing loss, vertigo, tinnitus, diplopia, hemifacial spasm, trigeminal neuralgia, and facial paresthesia. Twelve patients were managed by wait and see policy, and in this category, only one lesion showed growth during the follow-up. Depending upon size and location, 15 patients were surgically treated by infralabyrinthine approach (9 patients), infratemporal type B approach (3 patients), combined infratemporal type B transotic approach (2 patients), and transotic approach (1 patient). One recurrence was recorded during the follow-up.
CONCLUSIONS: Radiologic evaluation is required for diagnosis and management. Patients with good hearing can be treated by infralabyrinthine approach. Infratemporal fossa type B approach is advocated in patients with extensive disease and internal carotid artery involvement. Wait and see policy is recommended for asymptomatic cases. Drainage and permanent ventilation are the goals of treatment. Complete removal is indicated in selected cases where placement of drainage tube is not feasible.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19880030     DOI: 10.1016/j.amjoto.2008.08.007

Source DB:  PubMed          Journal:  Am J Otolaryngol        ISSN: 0196-0709            Impact factor:   1.808


  6 in total

1.  Petrous apex cholesterol granuloma: maintenance of drainage pathway, the histopathology of surgical management and histopathologic evidence for the exposed marrow theory.

Authors:  Michael Hoa; John W House; Fred H Linthicum
Journal:  Otol Neurotol       Date:  2012-08       Impact factor: 2.311

2.  Image-guided percutaneous aspiration and gelfoam treatment of petrous apex cholesterol granuloma: a new theory and method for diagnosis and treatment.

Authors:  Thomas C Lee; Deepak Raghavan; Hugh D Curtin
Journal:  J Neurol Surg B Skull Base       Date:  2013-04-26

Review 3.  Petrous apex cholesterol granuloma: pictorial review of radiological considerations in diagnosis and surgical histopathology.

Authors:  M Hoa; J W House; F H Linthicum; J L Go
Journal:  J Laryngol Otol       Date:  2013-02-26       Impact factor: 1.469

4.  Cholesterol Granuloma of the Petrous Apex: A 5-Year Review of Radiology Reports with Follow-Up of Progression and Treatment.

Authors:  Deepak Raghavan; Thomas C Lee; Hugh D Curtin
Journal:  J Neurol Surg B Skull Base       Date:  2015-01-21

5.  Usefulness of image guidance in the surgical treatment of petrous apex cholesterol granuloma.

Authors:  A Pietrantonio; G D'Andrea; I Famà; L Volpini; A Raco; M Barbara
Journal:  Case Rep Otolaryngol       Date:  2013-10-22

6.  Sixth Nerve Palsy from Cholesterol Granuloma of the Petrous Apex.

Authors:  Ségolène Roemer; Philippe Maeder; Roy Thomas Daniel; Aki Kawasaki
Journal:  Front Neurol       Date:  2017-02-15       Impact factor: 4.003

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.