Literature DB >> 19879836

Polycystins under pressure.

Bernd Nilius1.   

Abstract

All cells detect mechanical signals, but the underlying molecular mechanisms are unclear. In this issue of Cell, Sharif-Naeini et al. (2009) show that a candidate mechanosensing channel, TRPP2 (PKD2), unexpectedly acts as an inhibitor of a still-elusive stretch-activated cation channel in vascular smooth muscle cells.

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Year:  2009        PMID: 19879836     DOI: 10.1016/j.cell.2009.10.009

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  2 in total

1.  Pressing and squeezing with Piezos.

Authors:  Bernd Nilius
Journal:  EMBO Rep       Date:  2010-11-05       Impact factor: 8.807

Review 2.  From bone abnormalities to mineral metabolism dysregulation in autosomal dominant polycystic kidney disease.

Authors:  Djalila Mekahli; Justine Bacchetta
Journal:  Pediatr Nephrol       Date:  2013-01-24       Impact factor: 3.714

  2 in total

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