| Literature DB >> 19879071 |
Philipp Kaysser1, Wolf von Bomhard, Linda Dobrzykowski, Hermann Meyer.
Abstract
Recent cowpox virus (CPXV) infections of humans in Europe transmitted from cats and pet rats have risen public awareness of this rare zoonosis. Based on serosurveys wild rodents are regarded as primary reservoir hosts. Cats can become infected while hunting and could therefore serve as a sentinel for CPXV strains circulating in wild rodents. In a retrospective study we analysed 73 formalin-fixed paraffin-embedded skin samples from cats with a histologically proven CPXV infection. Specimens had been collected in different parts of Germany during 2000-2008. Following DNA extraction part of the hemagglutinin gene was amplified and sequenced from 72 samples. A phylogenetic analysis was inferred resulting in a total of 21 different CPXV genetic variants. The geographic distribution was imposed on a map. Copyright 2009 Elsevier B.V. All rights reserved.Entities:
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Year: 2009 PMID： 19879071 DOI： 10.1016/j.vetmic.2009.09.029
Source DB: PubMed Journal: Vet Microbiol ISSN： 0378-1135 Impact factor: 3.293