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Literature DB >> 19876720

Self-hardening calcium deficient hydroxyapatite/gelatine foams for bone regeneration.

Edgar B Montufar¹, Tania Traykova, Etienne Schacht, Luigi Ambrosio, Matteo Santin, Josep A Planell, Maria-Pau Ginebra.

Abstract

In this work gelatine was used as multifunctional additive to obtain injectable self-setting hydroxyapatite/gelatine composite foams for bone regeneration. The foaming and colloidal stabilization properties of gelatine are well known in food and pharmaceutical applications. Solid foams were obtained by foaming liquid gelatine solutions at 50 degrees C, followed by mixing them with a cement powder consisting of alpha tricalcium phosphate. Gelatine addition improved the cohesion and injectability of the cement paste. After setting the foamed paste transformed into a calcium deficient hydroxyapatite. The final porosity, pore interconnectivity and pore size were modulated by modifying the gelatine content in the liquid phase.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19876720 DOI： 10.1007/s10856-009-3918-7

Source DB: PubMed Journal: J Mater Sci Mater Med ISSN： 0957-4530 Impact factor: 3.896

15 in total

6. Blooming gelatin: an individual additive for enhancing nanoapatite precipitation, physical properties, and osteoblastic responses of nanostructured macroporous calcium phosphate bone cements.

Authors: Ziba Orshesh; Saeed Hesaraki; Ali Khanlarkhani
Journal: Int J Nanomedicine Date: 2017-01-23

6 in total

Self-hardening calcium deficient hydroxyapatite/gelatine foams for bone regeneration.

Review 1. Gelatin: a valuable protein for food and pharmaceutical industries: review.

Review 2. Tissue regeneration based on growth factor release.

3. Effect of added gelatin on the properties of calcium phosphate cement.

4. In vivo evaluation of an injectable Macroporous Calcium Phosphate Cement.

5. Setting reaction and hardening of an apatitic calcium phosphate cement.

6. Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug.

7. Preparation and compressive strength of alpha-tricalcium phosphate/gelatin gel composite cement.

8. Alpha-Tricalcium phosphate-gelatin composite cements.

9. Formation of macropores in calcium phosphate cement implants.

10. Fabrication of low temperature macroporous hydroxyapatite scaffolds by foaming and hydrolysis of an alpha-TCP paste.

1. Study of in vitro degradation of brushite cements scaffolds.

2. Antimicrobial Hydroxyapatite-Gelatin-Silica Composite Pastes with Tunable Setting Properties.

3. Polymeric additives to enhance the functional properties of calcium phosphate cements.

4. In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams.

5. Brushite foams--the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties.

6. Blooming gelatin: an individual additive for enhancing nanoapatite precipitation, physical properties, and osteoblastic responses of nanostructured macroporous calcium phosphate bone cements.