Literature DB >> 19876629

Impact of critical care reconfiguration and track-and-trigger outreach team intervention on outcomes of haematology patients requiring intensive care admission.

Syed W I Bokhari1, Talha Munir, Shabeeha Memon, Jenny L Byrne, Nigel H Russell, Martin Beed.   

Abstract

Patients with haematological disorders have previously been considered to have poor outcomes following admission to intensive care units. Although a number of haematology centres from outside the UK have now demonstrated improved outcomes, the continuing perception of poor outcomes in this patient group continues to adversely affect their chances of being admitted to some intensive care units (ICUs). Over the past 10 years, there have been many advances within the disciplines of both haematology and intensive care medicine. This study was done to assess outcomes and the impact of an early warning scoring system (EWS) and early involvement of ICU outreach teams. One hundred five haematology patients (haematopoietic stem cell transplant (HSCT) or non-HSCT) had 114 admissions to ICU between April 2006 and August 2008 which coincided with hospital-wide implementation of EWS. The survival to ICU discharge was 56 (53%). Thirty-three (33%) patients were alive at 6 months giving a 1-year survival of 31%. Of the 39 HSCT patients, nine were post-autologous and 30 post-allogeneic transplant. The survival to ICU discharge was 22 (56%) with 14 (36%) patients alive at 6 months. One year survival was 36%. Prior to the introduction of EWS and critical care outreach team (2004), survival to ICU discharge was 44% which has increased to 53% (2006-2008). This is despite an increase in mechanical ventilation in 2006-2008 (50%) as compared to 2004 (32%).The improvement in ICU survivorship was even more prominent in HSCT patients (37% in 2004 versus 56% in 2006-2008). There was a trend towards decreasing Acute Physiology and Chronic Health Evaluation scores with time, suggesting appropriate patients being identified earlier and having timely escalation of their treatment.

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Year:  2009        PMID: 19876629     DOI: 10.1007/s00277-009-0853-0

Source DB:  PubMed          Journal:  Ann Hematol        ISSN: 0939-5555            Impact factor:   3.673


  12 in total

Review 1.  Intensive care outcomes in adult hematopoietic stem cell transplantation patients.

Authors:  Ulas D Bayraktar; Joseph L Nates
Journal:  World J Clin Oncol       Date:  2016-02-10

2.  A critical care outreach team under strain - Evaluation of the service provided to patients with haematological malignancy during the Covid-19 pandemic.

Authors:  Emma Prower; Sophie Hadfield; Rohit Saha; Timothy Woo; Kar Mun Ang; Victoria Metaxa
Journal:  J Crit Care       Date:  2022-07-15       Impact factor: 4.298

3.  Short- and long-term outcomes of adult allogeneic hematopoietic stem cell transplant patients admitted to the intensive care unit in the peritransplant period.

Authors:  Sebastian Mayer; Stephen M Pastores; Elyn Riedel; Molly Maloy; Ann A Jakubowski
Journal:  Leuk Lymphoma       Date:  2016-06-27

4.  The role of a critical care outreach service in the management of patients with haematological malignancy.

Authors:  Leila Taheri; Rathai Anandanadesan; Hugues de Lavallade; Eirini Pagkalidou; Antonio Pagliuca; Ghulam Mufti; Georg Auzinger; Victoria Metaxa
Journal:  J Intensive Care Soc       Date:  2019-06-10

Review 5.  Ethical and clinical aspects of intensive care unit admission in patients with hematological malignancies: guidelines of the ethics commission of the French society of hematology.

Authors:  Sandra Malak; Jean-Jacques Sotto; Joël Ceccaldi; Philippe Colombat; Philippe Casassus; Dominique Jaulmes; Henri Rochant; Morgane Cheminant; Yvan Beaussant; Robert Zittoun; Dominique Bordessoule
Journal:  Adv Hematol       Date:  2014-10-01

6.  Implementing Obstetric Early Warning Systems.

Authors:  Alexander M Friedman; Mary L Campbell; Carolyn R Kline; Suzanne Wiesner; Mary E D'Alton; Laurence E Shields
Journal:  AJP Rep       Date:  2018-04-20

7.  Outcomes of hospitalized hematologic oncology patients receiving rapid response system activation for acute deterioration.

Authors:  Benjamin Gershkovich; Shannon M Fernando; Brent Herritt; Lana A Castellucci; Bram Rochwerg; Laveena Munshi; Sangeeta Mehta; Andrew J E Seely; Daniel I McIsaac; Alexandre Tran; Peter M Reardon; Peter Tanuseputro; Kwadwo Kyeremanteng
Journal:  Crit Care       Date:  2019-08-27       Impact factor: 9.097

8.  Long-term health related quality of life following intensive care during treatment for haematological malignancies.

Authors:  Maarten van Vliet; Mark van den Boogaard; J Peter Donnelly; Andrea W M Evers; Nicole M A Blijlevens; Peter Pickkers
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

9.  Improved intensive care unit survival for critically ill allogeneic haematopoietic stem cell transplant recipients following reduced intensity conditioning.

Authors:  William M Townsend; Ailsa Holroyd; Rachel Pearce; Stephen Mackinnon; Prakesh Naik; Anthony H Goldstone; David C Linch; Karl S Peggs; Kirsty J Thomson; Mervyn Singer; David C J Howell; Emma C Morris
Journal:  Br J Haematol       Date:  2013-03-18       Impact factor: 6.998

10.  Derivation and validation of modified early warning score plus SpO2/FiO2 score for predicting acute deterioration of patients with hematological malignancies.

Authors:  Ju-Ry Lee; Youn-Kyoung Jung; Hwa Jung Kim; Younsuck Koh; Chae-Man Lim; Sang-Bum Hong; Jin Won Huh
Journal:  Korean J Intern Med       Date:  2020-03-03       Impact factor: 2.884

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