Literature DB >> 19876049

Tomorrow, interrupted? Risk, ethics, and medical advance in gene transfer.

Jonathan Kimmelman1.   

Abstract

Mesh：

Year:  2009        PMID： 19876049      PMCID： PMC2835030          DOI： 10.1038/mt.2009.240

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  7 in total

1.  A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.

Authors:  Steven E Raper; Marc Yudkoff; Narendra Chirmule; Guang-Ping Gao; Fred Nunes; Ziv J Haskal; Emma E Furth; Kathleen J Propert; Michael B Robinson; Susan Magosin; Heather Simoes; Lisa Speicher; Joseph Hughes; John Tazelaar; Nelson A Wivel; James M Wilson; Mark L Batshaw
Journal:  Hum Gene Ther       Date:  2002-01-01       Impact factor: 5.695

2.  Gene therapy rising?

Authors:  Hannah Hoag
Journal:  Nature       Date:  2005-05-26       Impact factor: 49.962

3.  Does research ethics rest on a mistake? The common good, reasonable risk and social justice.

Authors:  Alex John London
Journal:  Am J Bioeth       Date:  2005       Impact factor: 11.229

4.  Medicine. A history lesson for stem cells.

Authors:  James M Wilson
Journal:  Science       Date:  2009-05-08       Impact factor: 47.728

Review 5.  Accepting risk in clinical research: is the gene therapy field becoming too risk-averse?

Authors:  Claire T Deakin; Ian E Alexander; Ian Kerridge
Journal:  Mol Ther       Date:  2009-09-22       Impact factor: 11.454

6.  Launching invasive, first-in-human trials against Parkinson's disease: ethical considerations.

Authors:  Jonathan Kimmelman; Alex John London; Bernard Ravina; Tim Ramsay; Mark Bernstein; Alan Fine; Frank W Stahnisch; Marina Elena Emborg
Journal:  Mov Disord       Date:  2009-10-15       Impact factor: 10.338

7.  Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.

Authors:  Michael G Kaplitt; Andrew Feigin; Chengke Tang; Helen L Fitzsimons; Paul Mattis; Patricia A Lawlor; Ross J Bland; Deborah Young; Kristin Strybing; David Eidelberg; Matthew J During
Journal:  Lancet       Date:  2007-06-23       Impact factor: 79.321
  7 in total
  2 in total

1.  Risk in clinical research: size matters!

Authors:  Pedro R Lowenstein
Journal:  Mol Ther       Date:  2009-11       Impact factor: 11.454

Review 2.  Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.

Authors:  Marina O'Reilly; Howard J Federoff; Yuman Fong; Donald B Kohn; Amy P Patterson; Nabil Ahmed; Aravind Asokan; Shannon E Boye; Ronald G Crystal; Satiro De Oliveira; Linda Gargiulo; Scott Q Harper; Yasuhiro Ikeda; Robert Jambou; Maureen Montgomery; Lawrence Prograis; Eugene Rosenthal; Daniel H Sterman; Luk H Vandenberghe; Laurie Zoloth; Mehrdad Abedi; Jennifer Adair; Prasad S Adusumilli; William F Goins; Jhanelle Gray; Paul Monahan; Leslie Popplewell; Miguel Sena-Esteves; Bakhos Tannous; Thomas Weber; William Wierda; Rashmi Gopal-Srivastava; Cheryl L McDonald; Daniel Rosenblum; Jacqueline Corrigan-Curay
Journal:  Hum Gene Ther       Date:  2014-06       Impact factor: 5.695
  2 in total

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