Literature DB >> 19875921

Intriguing novel abilities of Nutlin-3A: induction of cellular quiescence as opposed to cellular senescence--implications for chemotherapy.

Linda S Steelman, James A McCubrey.   

Abstract

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Year:  2009        PMID： 19875921

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  6 in total

1.  Persistent p21 expression after Nutlin-3a removal is associated with senescence-like arrest in 4N cells.

Authors:  Hong Shen; Carl G Maki
Journal:  J Biol Chem       Date:  2010-05-20       Impact factor: 5.157

2.  Rapamycin induces pluripotent genes associated with avoidance of replicative senescence.

Authors:  Tatiana V Pospelova; Tatiana V Bykova; Svetlana G Zubova; Natalia V Katolikova; Natalia M Yartzeva; Valery A Pospelov
Journal:  Cell Cycle       Date:  2013-12-02       Impact factor: 4.534

3.  Life or death: p53-induced apoptosis requires DNA binding cooperativity.

Authors:  Katharina Schlereth; Joël P Charles; Anne C Bretz; Thorsten Stiewe
Journal:  Cell Cycle       Date:  2010-10-11       Impact factor: 4.534

Review 4.  The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.

Authors:  Alberto M Martelli; Camilla Evangelisti; Francesca Chiarini; James A McCubrey
Journal:  Oncotarget       Date:  2010-06

5.  Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.

Authors:  Jackson R Taylor; Brian D Lehmann; William H Chappell; Stephen L Abrams; Linda S Steelman; James A McCubrey
Journal:  Oncotarget       Date:  2011-08

Review 6.  Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.

Authors:  William H Chappell; Linda S Steelman; Jacquelyn M Long; Ruth C Kempf; Stephen L Abrams; Richard A Franklin; Jörg Bäsecke; Franca Stivala; Marco Donia; Paolo Fagone; Graziella Malaponte; Maria C Mazzarino; Ferdinando Nicoletti; Massimo Libra; Danijela Maksimovic-Ivanic; Sanja Mijatovic; Giuseppe Montalto; Melchiorre Cervello; Piotr Laidler; Michele Milella; Agostino Tafuri; Antonio Bonati; Camilla Evangelisti; Lucio Cocco; Alberto M Martelli; James A McCubrey
Journal:  Oncotarget       Date:  2011-03
  6 in total

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