Literature DB >> 19875075

Expanding the repertoire of glycosynthases.

Lai-Xi Wang1.   

Abstract

As reported in this issue, Moracci and coworkers have now expanded the glycosynthase concept to two retaining alpha-L-fucosidases. The newly generated alpha-fucosynthases can use beta-L-fucosyl azide as donors for transglycosylation, enabling the synthesis of fucose-containing oligosaccharides.

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Year:  2009        PMID: 19875075      PMCID: PMC2787619          DOI: 10.1016/j.chembiol.2009.10.003

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  5 in total

Review 1.  Oligosaccharide synthesis by glycosynthases.

Authors:  Giuseppe Perugino; Antonio Trincone; Mosé Rossi; Marco Moracci
Journal:  Trends Biotechnol       Date:  2004-01       Impact factor: 19.536

Review 2.  Engineering of glycosidases and glycosyltransferases.

Authors:  Susan M Hancock; Mark D Vaughan; Stephen G Withers
Journal:  Curr Opin Chem Biol       Date:  2006-08-14       Impact factor: 8.822

3.  Alpha-glucosidase mutant catalyzes "alpha-glycosynthase"-type reaction.

Authors:  Masayuki Okuyama; Haruhide Mori; Kotomi Watanabe; Atsuo Kimura; Seiya Chiba
Journal:  Biosci Biotechnol Biochem       Date:  2002-04       Impact factor: 2.043

4.  1,2-alpha-l-Fucosynthase: a glycosynthase derived from an inverting alpha-glycosidase with an unusual reaction mechanism.

Authors:  Jun Wada; Yuji Honda; Masamichi Nagae; Ryuichi Kato; Soichi Wakatsuki; Takane Katayama; Hajime Taniguchi; Hidehiko Kumagai; Motomitsu Kitaoka; Kenji Yamamoto
Journal:  FEBS Lett       Date:  2008-10-07       Impact factor: 4.124

5.  Designer enzymes for glycosphingolipid synthesis by directed evolution.

Authors:  Susan M Hancock; Jamie R Rich; Matthew E C Caines; Natalie C J Strynadka; Stephen G Withers
Journal:  Nat Chem Biol       Date:  2009-07       Impact factor: 15.040

  5 in total
  1 in total

Review 1.  Chemoenzymatic Methods for the Synthesis of Glycoproteins.

Authors:  Chao Li; Lai-Xi Wang
Journal:  Chem Rev       Date:  2018-08-24       Impact factor: 60.622

  1 in total

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