BACKGROUND: Injection of botulinum toxin into certain areas of face that carry a high risk of ptosis (danger zone) needs caution in application. An example is the lateral forehead, particularly the lower portion. AIM: In this study, we evaluated the efficacy and safety of treating supraciliary wrinkles in the lower lateral forehead by injections of botulinum toxin at the temporal hairline, keeping a reasonable distance from danger zone. METHODS: In this randomized clinical trial, 40 women (mean age 35 years) were selected and divided into two groups, A and B. both groups were treated with botulinum toxin to treat wrinkles in the frown area, as well as frontal lines and lateral canthus lines. Group B received extra injections at each temporal line for treatment of supraciliary wrinkles. RESULTS: There was a significant difference in total wrinkle number and mean number of wrinkles between the two groups after injections (paired t-test, P < 0.01). No ptosis was seen in either group. CONCLUSIONS: Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective.
RCT Entities:
BACKGROUND: Injection of botulinum toxin into certain areas of face that carry a high risk of ptosis (danger zone) needs caution in application. An example is the lateral forehead, particularly the lower portion. AIM: In this study, we evaluated the efficacy and safety of treating supraciliary wrinkles in the lower lateral forehead by injections of botulinum toxin at the temporal hairline, keeping a reasonable distance from danger zone. METHODS: In this randomized clinical trial, 40 women (mean age 35 years) were selected and divided into two groups, A and B. both groups were treated with botulinum toxin to treat wrinkles in the frown area, as well as frontal lines and lateral canthus lines. Group B received extra injections at each temporal line for treatment of supraciliary wrinkles. RESULTS: There was a significant difference in total wrinkle number and mean number of wrinkles between the two groups after injections (paired t-test, P < 0.01). No ptosis was seen in either group. CONCLUSIONS: Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective.