Literature DB >> 19874222

Anti-necrosis potential of polyphenols against snake venoms.

Jiraporn Leanpolchareanchai1, Pimolpan Pithayanukul, Rapepol Bavovada.   

Abstract

Polyphenols from the extracts of Areca catechu L. and Quercus infectoria Oliv. inhibited phospholipase A(2), proteases, hyaluronidase and L-amino acid oxidase of Naja naja kaouthia Lesson (NK) and Calloselasma rhodostoma Kuhl (CR) venoms by in vitro tests. Both extracts inhibited the hemorrhagic activity of CR venom and the dermonecrotic activity of NK venom by in vivo tests. The inhibitory activity of plant polyphenols against local tissue necrosis induced by snake venoms may be caused by inhibition of inflammatory reactions, hemorrhage, and necrosis. The result implies the therapeutic potential of plant polyphenols against necrosis in snakebite victims.

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Year:  2009        PMID： 19874222     DOI： 10.3109/08923970902821702

Source DB:  PubMed          Journal:  Immunopharmacol Immunotoxicol        ISSN： 0892-3973            Impact factor:   2.730


  7 in total

1.  Do herbal medicines have potential for managing snake bite envenomation?

Authors:  Y K Gupta; S S Peshin
Journal:  Toxicol Int       Date:  2012-05

2.  Bordonein-L, a new L-amino acid oxidase from Crotalus durissus terrificus snake venom: isolation, preliminary characterization and enzyme stability.

Authors:  Karla C F Bordon; Gisele A Wiezel; Hamilton Cabral; Eliane C Arantes
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2015-08-13

3.  Snakebite Envenomation, Attitudes, and Behavior toward Snakes in Banten, Indonesia.

Authors:  Linda T Uyeda; Entang Iskandar; Aaron J Wirsing; Randall C Kyes
Journal:  Animals (Basel)       Date:  2022-08-11       Impact factor: 3.231

4.  Inhibitory effect of plant Manilkara subsericea against biological activities of Lachesis muta snake venom.

Authors:  Eduardo Coriolano De Oliveira; Caio Pinho Fernandes; Eladio Flores Sanchez; Leandro Rocha; André Lopes Fuly
Journal:  Biomed Res Int       Date:  2014-01-08       Impact factor: 3.411

5.  In vitro screening and evaluation of antivenom phytochemicals from Azima tetracantha Lam. leaves against Bungarus caeruleus and Vipera russelli.

Authors:  Bhavya Janardhan; Vineetha M Shrikanth; Kiran K Mirajkar; Sunil S More
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2014-04-01

6.  Molecular docking studies and anti-snake venom metalloproteinase activity of Thai mango seed kernel extract.

Authors:  Pimolpan Pithayanukul; Jiraporn Leanpolchareanchai; Patchreenart Saparpakorn
Journal:  Molecules       Date:  2009-08-27       Impact factor: 4.411

7.  Molecular docking studies and anti-enzymatic activities of Thai mango seed kernel extract against snake venoms.

Authors:  Jiraporn Leanpolchareanchai; Pimolpan Pithayanukul; Rapepol Bavovada; Patchreenart Saparpakorn
Journal:  Molecules       Date:  2009-03-31       Impact factor: 4.411
  7 in total

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