Literature DB >> 19874210

High-resolution optical coherence tomography correlates in ischemic radiation retinopathy.

Rajiv Raman1, Swakshyar Saumya Pal, Tandava Krishnan, Gella Laxmi, Nishant Radke, Tarun Sharma.   

Abstract

PURPOSE: To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT).
METHODS: We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were done using information both at the fovea and 2.5 mm temporal to the fovea.
RESULTS: The layers that were reduced in thickness included the inner plexiform layer (47 microm vs. 74 microm), the inner nuclear layer (17 microm vs. 48 microm), and the outer plexiform layer (25 microm vs. 45 microm), whereas the layers with comparable thickness included the nerve fiber layer (24 microm vs. 25 microm), the outer nuclear layer (42 microm vs. 43 microm), the outer segment-inner segment junction (52 microm vs. 54 microm), and the retinal pigment epithelium (RPE) choriocapillaris layer (30 microm vs. 28 microm).
CONCLUSION: This report suggests that the radiation-induced damage was confined to the inner layers of the retina. However, secondary outer retinal layer changes may also occur, as suggested by functional derangements.

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Year:  2010        PMID: 19874210     DOI: 10.3109/15569520903331674

Source DB:  PubMed          Journal:  Cutan Ocul Toxicol        ISSN: 1556-9527            Impact factor:   1.820


  1 in total

1.  Evaluation of early changes of macular function and morphology by multifocal electroretinograms in patients with nasopharyngeal carcinoma after radiotherapy.

Authors:  Haijun Gong; Yuanlin Tang; Jianhui Xiao; Yimin Liu; Rui Zeng; Zijing Li; Si Zhang; Yuqing Lan
Journal:  Doc Ophthalmol       Date:  2019-02-09       Impact factor: 2.379

  1 in total

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