| Literature DB >> 19873104 |
Abstract
A statistical examination of the available data on the ratio of antibody to antigen in specific precipitates made at or near the optimum shows a definite correlation between the ratio and the molecular weight of antigen (regression coefficient = -0.529 (+/-0.014)). The authors' assumption that at this point the antigen molecules are just about covered by a layer of antibody behaving as contiguous spherical ("Svedberg") units of weight 35,200 leads to predicted ratios that in general agree well with those found, though individual experimental determinations may deviate considerably.Year: 1939 PMID: 19873104 PMCID: PMC2141996 DOI: 10.1085/jgp.22.3.281
Source DB: PubMed Journal: J Gen Physiol ISSN: 0022-1295 Impact factor: 4.086