Literature DB >> 19871610

ANTIBODY FORMATION IN MEN FOLLOWING INJECTION OF FOUR TYPE-SPECIFIC POLYSACCHARIDES OF PNEUMOCOCCUS.

M Heidelberger1, C M Macleod, R G Hodges, W G Bernhard, M M di Lapi.   

Abstract

1. Random selections of the sera of trainees injected 2 months previously with the specific polysaccharides of Types I, II, V, and VII pneumococci contained quantities of antibody to Types I, II, and VII sufficient to account for the favorable results of the immunization procedure. 2. As in earlier studies, the levels of the antibody for the C polysaccharide remained relatively constant before and after the injections. 3. The serum from the preliminary bleedings often contained antibody to the Type VII polysaccharide. This remained relatively constant in a control group injected with saline.

Entities:  

Keywords:  ANTIGENS AND ANTIBODIES; PNEUMOCOCCI/immunity; SACCHARIDES/poly-

Mesh:

Substances:

Year:  1947        PMID: 19871610      PMCID: PMC2135695          DOI: 10.1084/jem.85.3.227

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  2 in total

1.  QUANTITATIVE MICRO-ESTIMATION OF ANTIBODIES IN THE SERA OF MAN AND OTHER ANIMALS.

Authors:  M Heidelberger; C F Macpherson
Journal:  Science       Date:  1943-04-30       Impact factor: 47.728

2.  PREVENTION OF PNEUMOCOCCAL PNEUMONIA BY IMMUNIZATION WITH SPECIFIC CAPSULAR POLYSACCHARIDES.

Authors:  C M Macleod; R G Hodges; M Heidelberger; W G Bernhard
Journal:  J Exp Med       Date:  1945-11-30       Impact factor: 14.307

  2 in total
  3 in total

Review 1.  Pneumococcal polysaccharide vaccines: indications, efficacy and recommendations.

Authors:  G A Bruyn; R van Furth
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-11       Impact factor: 3.267

2.  IMPROVED METHODS FOR THE PREPARATION OF THE SPECIFIC POLYSACCHARIDES OF PNEUMOCOCCUS.

Authors:  M Heidelberger; C M Macleod; H Markowitz; A S Roe
Journal:  J Exp Med       Date:  1950-03-31       Impact factor: 14.307

3.  A quantitative antibody response of man to infection or vaccination with Pasteurella tularensis.

Authors:  M M ALEXANDER
Journal:  J Exp Med       Date:  1950-07-01       Impact factor: 14.307

  3 in total

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