Literature DB >> 19871414

STUDIES IN HUMAN IMMUNIZATION AGAINST INFLUENZA : DURATION OF IMMUNITY INDUCED BY INACTIVE VIRUS.

G K Hirst1, E R Rickard, W F Friedewald.   

Abstract

The administration to human beings of formalin-killed influenza virus, concentrated from allantoic fluid, resulted in a high order of antibody response within 2 weeks after injection. Even after 1 year the great majority of individuals vaccinated had antibody levels considerably above their prevaccination titer for the PR8, Lee, and a current 1943 strain. An investigation of the occurrence of epidemic influenza A in seven widely separated populations, 1 year after vaccination of part of these groups, showed that the attack rate among vaccinated persons was consistently lower than that of control individuals. The average reduction in attack rate was of the order of 35 per cent.

Entities:  

Year:  1944        PMID： 19871414      PMCID： PMC2135471          DOI： 10.1084/jem.80.4.265

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  7 in total

1.  AN EPIDEMIC OF INFLUENZA. RESULTS OF PROPHYLACTIC INOCULATION OF A COMPLEX INFLUENZA A-DISTEMPER VACCINE.

Authors:  J W Brown; M D Eaton; G Meiklejohn; J B Lagen; W J Kerr
Journal:  J Clin Invest       Date:  1941-11       Impact factor: 14.808

2.  A SIMPLIFIED PROCEDURE FOR THE CONCENTRATION AND PURIFICATION OF INFLUENZA VIRUS.

Authors:  T Francis; J E Salk
Journal:  Science       Date:  1942-11-27       Impact factor: 47.728

3.  ADSORPTION OF INFLUENZA HEMAGGLUTININS AND VIRUS BY RED BLOOD CELLS.

Authors:  G K Hirst
Journal:  J Exp Med       Date:  1942-08-01       Impact factor: 14.307

4.  APPARATUS FOR FREEZING AND DRYING VIRUS IN LARGE QUANTITIES UNDER UNIFORM CONDITIONS.

Authors:  J H Bauer; E G Pickels
Journal:  J Exp Med       Date:  1940-01-01       Impact factor: 14.307

5.  A COMPLEX VACCINE AGAINST INFLUENZA A VIRUS : QUANTITATIVE ANALYSIS OF THE ANTIBODY RESPONSE PRODUCED IN MAN.

Authors:  F L Horsfall; E H Lennette; E R Rickard
Journal:  J Exp Med       Date:  1941-02-28       Impact factor: 14.307

6.  ANTIBODY RESPONSE OF HUMAN BEINGS FOLLOWING VACCINATION WITH INFLUENZA VIRUSES.

Authors:  G K Hirst; E R Rickard; L Whitman; F L Horsfall
Journal:  J Exp Med       Date:  1942-05-01       Impact factor: 14.307

7.  THE IMMUNOLOGICAL RESPONSE TO INFLUENZA VIRUS INFECTION AS MEASURED BY THE COMPLEMENT FIXATION TEST : RELATION OF THE COMPLEMENT-FIXING ANTIGEN TO THE VIRUS PARTICLE.

Authors:  W F Friedewald
Journal:  J Exp Med       Date:  1943-11-01       Impact factor: 14.307
  7 in total
  2 in total

1.  Competitive detection of influenza neutralizing antibodies using a novel bivalent fluorescence-based microneutralization assay (BiFMA).

Authors:  Steven F Baker; Aitor Nogales; Felix W Santiago; David J Topham; Luis Martínez-Sobrido
Journal:  Vaccine       Date:  2015-06-01       Impact factor: 3.641

2.  THE PREPARATION AND PROPERTIES OF INFLUENZA VIRUS VACCINES CONCENTRATED AND PURIFIED BY DIFFERENTIAL CENTRIFUGATION.

Authors:  W M Stanley
Journal:  J Exp Med       Date:  1945-02-01       Impact factor: 14.307
  2 in total

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