| Literature DB >> 19871319 |
R J Dubos1, J H Straus, C Pierce.
Abstract
1. Anti-Shiga bacteriophage injected into the general circulation can multiply in the brain of mice infected intracerebrally with Shigella dysenteriae. 2. Under proper conditions, the injection of active bacteriophage into the general circulation can protect mice against an otherwise fatal intracerebral infection with Shigella dysenteriae. 3. The protection so induced appears to depend upon the early establishment of a high bacteriophage level in the infected animal.Entities:
Year: 1943 PMID: 19871319 PMCID: PMC2135327 DOI: 10.1084/jem.78.3.161
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307