| Literature DB >> 19871131 |
Abstract
Acute renal hypertension is produced by the injection of the amino acid dopa (l-dihydroxyphenylalanine) into the partially or completely ischemic kidney of the cat. Evidence is presented suggesting that the rise in blood pressure following the injection of dopa is caused by its conversion into hydroxytyramine, a pressor amine. Kidneys with normal blood flow fail to transform dopa into a pressor substance.Entities:
Year: 1941 PMID: 19871131 PMCID: PMC2135177 DOI: 10.1084/jem.74.3.235
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307