Literature DB >> 19871106

QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : II. THE INTERRELATION OF COMPLEMENT WITH ANTIGEN-ANTIBODY COMPOUNDS AND WITH SENSITIZED RED CELLS.

M Heidelberger1, A J Weil, H P Treffers.   

Abstract

1. The molecular quantities of hemolysin and complement combining component or components (C'1) involved in hemolysis have been calculated on the basis of new, quantitative, absolute methods of analysis. 2. Molecular combining ratios between antigen, antibody, and C'1 have been established. 3. The data are shown to be in accord with the theory of combination of multivalent antigen with multivalent antibody. 4. The fixation of complement by antigen-antibody combination is qualitatively and quantitatively accounted for on this basis.

Entities:  

Year:  1941        PMID： 19871106      PMCID： PMC2135160          DOI： 10.1084/jem.73.6.695

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  11 in total

1.  A QUANTITATIVE THEORY OF THE PRECIPITIN REACTION : III. THE REACTION BETWEEN CRYSTALLINE EGG ALBUMIN AND ITS HOMOLOGOUS ANTIBODY.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1935-10-31       Impact factor: 14.307

2.  QUANTITATIVE STUDIES ON ANTIBODY PURIFICATION : II. THE DISSOCIATION OF ANTIBODY FROM PNEUMOCOCCUS SPECIFIC PRECIPITATES AND SPECIFICALLY AGGLUTINATED PNEUMOCOCCI.

Authors:  M Heidelberger; E A Kabat
Journal:  J Exp Med       Date:  1938-01-31       Impact factor: 14.307

3.  THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : III. A QUANTITATIVE STUDY AND A THEORY OF THE REACTION MECHANISM.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1935-03-31       Impact factor: 14.307

4.  CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : III. A REACTION MECHANISM AND A QUANTITATIVE THEORY.

Authors:  M Heidelberger; E A Kabat
Journal:  J Exp Med       Date:  1937-05-31       Impact factor: 14.307

5.  QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : I. A METHOD.

Authors:  M Heidelberger
Journal:  J Exp Med       Date:  1941-05-31       Impact factor: 14.307

6.  THE MOLECULAR WEIGHT OF ANTIBODIES.

Authors:  M Heidelberger; K O Pedersen
Journal:  J Exp Med       Date:  1937-02-28       Impact factor: 14.307

7.  A QUANTITATIVE THEORY OF THE PRECIPITIN REACTION : VII. THE EGG ALBUMIN-ANTIBODY REACTION IN ANTISERA FROM THE RABBIT AND HORSE.

Authors:  M Heidelberger; H P Treffers; M Mayer
Journal:  J Exp Med       Date:  1940-01-31       Impact factor: 14.307

8.  THE COMPLEMENT FIXATION REACTION WITH PNEUMOCOCCUS CAPSULAR POLYSACCHARIDE.

Authors:  K Goodner; F L Horsfall
Journal:  J Exp Med       Date:  1936-07-31       Impact factor: 14.307

9.  THE MOLECULAR WEIGHT OF ANTIBODIES.

Authors:  E A Kabat
Journal:  J Exp Med       Date:  1939-01-01       Impact factor: 14.307

10.  A QUANTITATIVE THEORY OF THE PRECIPITIN REACTION : IV. THE REACTION OF PNEUMOCOCCUS SPECIFIC POLYSACCHARIDES WITH HOMOLOGOUS RABBIT ANTISERA.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1937-04-30       Impact factor: 14.307
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  11 in total

1.  [Methodological and clinical studies on the properdin system. III. Studies on the behavior of 4 complement components after major gynecological operations].

Authors:  G SCHUMACHER; H D SCHLUMBERGER
Journal:  Arch Gynakol       Date:  1961

2.  [Demonstration of complement-binding structures in Aschoff's nodes of surgically removed heart auricles].

Authors:  K KUEPPER; E LANGER; P KLEIN
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1961

Review 3.  The role of antibody in the activation of the alternative complement pathway.

Authors:  W D Ratnoff; D T Fearon; K F Austen
Journal:  Springer Semin Immunopathol       Date:  1983

4.  THE PNEUMOCOCCAL CAPSULAR SWELLING REACTION, STUDIED WITH THE AID OF THE ELECTRON MICROSCOPE.

Authors:  S Mudd; F Heinmets; T F Anderson
Journal:  J Exp Med       Date:  1943-11-01       Impact factor: 14.307

5.  Kinetic studies on immune hemolysis; a method.

Authors:  M M MAYER; C C CROFT; M M GRAY
Journal:  J Exp Med       Date:  1948-10-01       Impact factor: 14.307

6.  Experimental hypersensitivity in the rabbit; effect of inhibition of antibody formation by X-radiation and nitrogen mustards on the histologic and serologic sequences, and on the behavior of serum complement, following single large injections of foreign Proteins.

Authors:  L SCHWAB; F C MOLL; T HALL; H BREAN; M KIRK; C van Z HAWN; C A HANEWAY
Journal:  J Exp Med       Date:  1950-05-01       Impact factor: 14.307

7.  THE ROLE OF THE COMPONENTS OF COMPLEMENT IN SPECIFIC IMMUNE FIXATION.

Authors:  L Pillemer; S Seifter; E E Ecker
Journal:  J Exp Med       Date:  1942-04-01       Impact factor: 14.307

8.  QUANTITATIVE CHEMICAL STUDIES ON HEMOLYSINS : I. THE ESTIMATION OF TOTAL ANTIBODY IN ANTISERA TO SHEEP ERYTHROCYTES AND STROMATA.

Authors:  M Heidelberger; H P Treffers
Journal:  J Gen Physiol       Date:  1942-03-20       Impact factor: 4.086

9.  QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : III. UPTAKE OF COMPLEMENT NITROGEN UNDER VARYING EXPERIMENTAL CONDITIONS.

Authors:  M Heidelberger; M Rocha E Silva; M Mayer
Journal:  J Exp Med       Date:  1941-09-30       Impact factor: 14.307

10.  QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : IV. ADDITION OF HUMAN COMPLEMENT TO SPECIFIC PRECIPITATES.

Authors:  M Heidelberger; M Mayer
Journal:  J Exp Med       Date:  1942-03-01       Impact factor: 14.307
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