Literature DB >> 19871043

THE MECHANISM BY WHICH EXPERIMENTAL NEPHRITIS IS PRODUCED IN RABBITS INJECTED WITH NEPHROTOXIC DUCK SERUM.

C F Kay1.   

Abstract

1. Glomerulonephritis was produced in rabbits by the injection of antirabbit-kidney duck serum. 2. The clinical and pathologic characteristics of the disease are discussed. 3. It was found possible by appropriate means either to accelerate the development of the nephritis or to prevent its appearance entirely. 4. An apparent correlation was found between the development of the nephritis and the formation of antibodies to duck serum by the injected rabbit. 5. The generally accepted concept of the mechanism of the disease does not appear to be in accordance with the facts here observed. A new hypothesis is presented.

Entities:  

Year:  1940        PMID： 19871043      PMCID： PMC2135031          DOI： 10.1084/jem.72.5.559

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  3 in total

1.  ACUTE EXPERIMENTAL GLOMERULAR NEPHRITIS IN RABBITS: A CORRELATION OF MORPHOLOGICAL AND FUNCTIONAL CHANGES.

Authors:  W E Ehrich; R E Wolf; G M Bartol
Journal:  J Exp Med       Date:  1938-04-30       Impact factor: 14.307

2.  EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : I. PREPARATION AND IMMUNOLOGICAL STUDIES OF NEPHROTOXIN.

Authors:  J E Smadel
Journal:  J Exp Med       Date:  1936-11-30       Impact factor: 14.307

3.  EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : II. CLINICAL AND FUNCTIONAL STUDIES.

Authors:  J E Smadel; L E Farr
Journal:  J Exp Med       Date:  1937-03-31       Impact factor: 14.307
  3 in total
  12 in total

1.  [Animal experimental studies on the problem of natural resistance to bacterial infections. IV. The effect of staphylococcal toxins on white rats pretreated with foreign protein].

Authors:  M KIENITZ; W RITZERFELD; W HUETHER; J RATH
Journal:  Z Hyg Infektionskr       Date:  1961

2.  [The effect of heterologous tissue cells (Niehans' renal dry cells) on the Masugi's nephritis in rat].

Authors:  K O VORLAENDER; W FITTING; G GIERLICH
Journal:  Klin Wochenschr       Date:  1954-12-01

3.  [The problem of auto-antibodies].

Authors:  H HARDERS
Journal:  Klin Wochenschr       Date:  1954-09-01

4.  [Experimental nephritis in animals with special reference to the so-called Calvelti's nephritis].

Authors:  A BOHLE; H J KRECKE; H KLEINMAIER; K GOERGEN
Journal:  Arch Kreislaufforsch       Date:  1954-12

5.  [The problem of organ-specific antibodies].

Authors:  H OTTO
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1954

6.  [Humoral factors in the pathogenesis of the human hypertension].

Authors:  J MOELLER
Journal:  Arch Kreislaufforsch       Date:  1952-09

7.  [The effect of heparin and prednisolone on experimental glomerunephritis].

Authors:  G Schütterle; D Platt
Journal:  Klin Wochenschr       Date:  1970-02-01

Review 8.  Glomerular antigens in glomerulonephritis.

Authors:  T J Neale; C B Wilson
Journal:  Springer Semin Immunopathol       Date:  1982

9.  Experimental hypersensitivity in the rabbit; effect of inhibition of antibody formation by X-radiation and nitrogen mustards on the histologic and serologic sequences, and on the behavior of serum complement, following single large injections of foreign Proteins.

Authors:  L SCHWAB; F C MOLL; T HALL; H BREAN; M KIRK; C van Z HAWN; C A HANEWAY
Journal:  J Exp Med       Date:  1950-05-01       Impact factor: 14.307

10.  Analytical pathology. IV. The role of localized antibodies in the pathogenesis of nephrotoxic nephritis in the rat.

Authors:  L G ORTEGA; R C MELLORS
Journal:  J Exp Med       Date:  1956-07-01       Impact factor: 14.307
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