Literature DB >> 19870709

DEMONSTRATION OF TYPE SPECIFIC PROTEINS IN EXTRACTS OF FUSOBACTERIA.

C Weiss1, D G Mercado.   

Abstract

1. The classification of fusobacteria into types, as suggested by Slanetz and Rettger on the basis of their cultural and biochemical characteristics, was confirmed. The following additional data are presented: the behavior of types I, II, and III in several previously untested carbohydrates; the final pH in 1 per cent glucose broth; the hydrolysis of starch; the failure to decompose sodium hippurate and citrates; the absence of pathogenicity for several types of experimental animals; and the absence of fibrinolysin and of proteolytic enzymes. 2. By the use of a technic described in the text, it was possible to grow the anaerobic fusobacteria in mass cultures. 3. With the methods of Heidelberger and Kendall, immunologically type specific proteins were extracted from fusobacteria types I, II, and III. This observation, which is in a sense an extension of the work of Lancefield on Streptococcus hemolyticus, group A, represents the second instance of a bacterial protein functioning as a determinant of bacterial types. 4. Preliminary data indicate that group specificity depends upon a carbohydrate which is extractable by the methods of Heidelberger and Avery.

Entities:  

Year:  1938        PMID: 19870709      PMCID: PMC2133543          DOI: 10.1084/jem.67.1.49

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  8 in total

1.  A Systematic Study of the Fusiform Bacteria.

Authors:  L W Slanetz; L F Rettger
Journal:  J Bacteriol       Date:  1933-12       Impact factor: 3.490

2.  THE SEROLOGICAL CLASSIFICATION OF FUSIFORM BACILLI.

Authors:  P L Varney
Journal:  J Bacteriol       Date:  1927-04       Impact factor: 3.490

3.  THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HAEMOLYTICUS : I. DEMONSTRATION OF A TYPE-SPECIFIC SUBSTANCE IN EXTRACTS OF STREPTOCOCCUS HAEMOLYTICUS.

Authors:  R C Lancefield
Journal:  J Exp Med       Date:  1928-01-01       Impact factor: 14.307

4.  THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS.

Authors:  M Heidelberger; O T Avery
Journal:  J Exp Med       Date:  1923-06-30       Impact factor: 14.307

5.  PROTEIN FRACTIONS OF A SCARLATINAL STRAIN OF STREPTOCOCCUS HEMOLYTICUS.

Authors:  M Heidelberger; F E Kendall
Journal:  J Exp Med       Date:  1931-09-30       Impact factor: 14.307

6.  THE FIBRINOLYTIC ACTIVITY OF HEMOLYTIC STREPTOCOCCI.

Authors:  W S Tillett; R L Garner
Journal:  J Exp Med       Date:  1933-09-30       Impact factor: 14.307

7.  A SEROLOGICAL DIFFERENTIATION OF SPECIFIC TYPES OF BOVINE HEMOLYTIC STREPTOCOCCI (GROUP B).

Authors:  R C Lancefield
Journal:  J Exp Med       Date:  1934-03-31       Impact factor: 14.307

8.  A SEROLOGICAL DIFFERENTIATION OF HUMAN AND OTHER GROUPS OF HEMOLYTIC STREPTOCOCCI.

Authors:  R C Lancefield
Journal:  J Exp Med       Date:  1933-03-31       Impact factor: 14.307

  8 in total

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