| Literature DB >> 19870630 |
L D Fothergill1, J H Dingle, C A Chandler.
Abstract
1. It has been shown that the ability of virulent S. influenzae to kill mice is enhanced by suspending the organism in mucin. 2. The occurrence of a true infection characterized by in vivo multiplication of the organism has been established. 3. The necessity for using a pure inbred strain of mice for this type of study has been confirmed. 4. The increase in mucin virulence of a strain of H. influenzae by repeated passage through mice has been shown. 5. The usefulness of this method in passive immunization studies has been demonstrated.Entities:
Year: 1937 PMID: 19870630 PMCID: PMC2133510 DOI: 10.1084/jem.65.5.721
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307