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Literature DB >> 19870498

STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS.

Abstract

The degree of immunization and sensitization of rabbits following injections of beef lens is markedly increased when the animals are under the influence of staphylotoxin. Since the effect of the latter is exerted when the two substances are introduced separately into the same tissues with several hours elapsing between injections, or into different veins, it appears that an intimate association of them is unnecessary. A stimulating action of the toxin on the antibody-forming cells is a more probable explanation of the phenomena observed. Animals actively immune to staphylotoxin fail to show any synergic effect of this toxin when introduced with beef lens. Neutralization of the toxin in vitro, on the other hand, fails to eliminate this stimulating effect.

Entities: Species

Year: 1936 PMID： 19870498 PMCID： PMC2133363 DOI： 10.1084/jem.63.5.703

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

5 in total

1. On Serum Anaphylaxis in the Guinea-Pig.

Authors: F P Gay; E E Southard
Journal: J Med Res Date: 1907-05

2. PRODUCTION OF HETEROGENETIC ANTIBODIES WITH MIXTURES OF THE BINDING PART OF THE ANTIGEN AND PROTEIN.

Authors: K Landsteiner; S Simms
Journal: J Exp Med Date: 1923-07-31 Impact factor: 14.307

3. THE INDUCED SUSCEPTIBILITY OF THE GUINEA-PIG TO THE TOXIC ACTION OF THE BLOOD SERUM OF THE HORSE.

Authors: P A Lewis
Journal: J Exp Med Date: 1908-01-01 Impact factor: 14.307

4. THE EFFECT OF ANTECEDENT INFECTION AND IMMUNIZATION WITH STREPTOCOCCI UPON THE REACTIVITY OF RABBITS TO HORSE SERUM.

Authors: M P Schultz; H F Swift
Journal: J Exp Med Date: 1934-08-31 Impact factor: 14.307

5. ALLERGIC IRRITABILITY : THE FORMATION OF ANTI-SHEEP HEMOLYTIC AMBOCEPTOR IN THE NORMAL AND TUBERCULOUS GUINEA PIG.

Authors: P A Lewis; D Loomis
Journal: J Exp Med Date: 1924-09-30 Impact factor: 14.307

5 in total

9 in total

1. [CONTRIBUTIONS TO THE STUDY OF AUTOIMMUNIZATION AND THE ROLE OF THIS PHENOMENON IN THE PATHOGENESIS OF SOME PATHOLOGICAL SKIN MANIFESTATIONS. I. EXPERIMENTAL RESEARCH IN CONNECTION WITH THE DEMONSTRATION OF THE DEVELOPMENT OF SOME ORGAN ANTIBODIES].

Authors: S G NICOLAU; A BAEDAENOIU; M GAVRILESCU
Journal: Arch Klin Exp Dermatol Date: 1964-10-20

6. Studies on the O antigen of Salmonella typhosa. V. Enhancement of antibody response to protein antigens by the purified lipopolysaccharide.

Authors: A G JOHNSON; S GAINES; M LANDY
Journal: J Exp Med Date: 1956-02-01 Impact factor: 14.307

7. HETEROGENETIC ANTIBODIES IN ACUTE HEPATITIS.

Authors: M D Eaton; W D Murphy; V L Hanford
Journal: J Exp Med Date: 1944-05-01 Impact factor: 14.307

8. STUDIES IN SYNERGY : SYNERGIC STIMULATING EFFECT OF HYPERSENSITIVITY TO FOREIGN PROTEIN AND TO BACTERIA.

Authors: H F Swift; M P Schultz
Journal: J Exp Med Date: 1936-04-30 Impact factor: 14.307

9. STUDIES IN SENSITIZATION TO SKIN : I. THE PRODUCTION OF ANTIBODIES TO SKIN BY MEANS OF THE SYNERGISTIC ACTION OF HOMOLOGOUS SKIN ANTIGEN AND STAPHYLOCOCCUS TOXIN.

Authors: R Hecht; M B Sulzberger; H Weil
Journal: J Exp Med Date: 1943-07-01 Impact factor: 14.307