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Literature DB >> 19870385

ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS.

Abstract

The repeated intramuscular injections of aqueous emulsions and alcohol-ether extracts of sterile normal rabbit brains in some manner produced pathological changes accompanied by myelin destruction in the brains of 7 of 8 monkeys (Macacus rhesus). Eight, control monkeys remained well. Cultures from the involved brains remained sterile, and no transmissible agent was demonstrated by means of intracerebral inoculations of emulsions of bits of the brains into monkeys, rabbits, guinea pigs, and white mice.

Entities: Chemical Species

Year: 1935 PMID： 19870385 PMCID： PMC2133246 DOI： 10.1084/jem.61.5.689

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

2 in total

1. Standardisation of human chorionic gonadotropin, hCG subunits, and pregnancy tests.

Authors: M C Stuart; L Lazarus
Journal: Lancet Date: 1982-05-15 Impact factor: 79.321

2. THE ANTIBODY RESPONSE OF RABBITS TO INJECTIONS OF EMULSIONS AND EXTRACTS OF HOMOLOGOUS BRAIN.

Authors: F F Schwentker; T M Rivers
Journal: J Exp Med Date: 1934-10-31 Impact factor: 14.307

2 in total

71 in total

1. The relevance of animal models in multiple sclerosis research.

Authors: Aleksandar Denic; Aaron J Johnson; Allan J Bieber; Arthur E Warrington; Moses Rodriguez; Istvan Pirko
Journal: Pathophysiology Date: 2011-02

Review 2. Multiple sclerosis and its animal models: the role of the major histocompatibility complex and the T cell receptor repertoire.

Authors: L Steinman
Journal: Springer Semin Immunopathol Date: 1992

3. Reviewing multiple sclerosis.

Authors: A Compston
Journal: Postgrad Med J Date: 1992-07 Impact factor: 2.401

4. [VIROLOGICAL ASPECTS OF MULTIPLE SCLEROSIS].

Authors: E PETTE; H PETTE
Journal: Dtsch Z Nervenheilkd Date: 1963-08-14

5. [CONTRIBUTIONS TO THE STUDY OF AUTOIMMUNIZATION AND THE ROLE OF THIS PHENOMENON IN THE PATHOGENESIS OF SOME PATHOLOGICAL SKIN MANIFESTATIONS. I. EXPERIMENTAL RESEARCH IN CONNECTION WITH THE DEMONSTRATION OF THE DEVELOPMENT OF SOME ORGAN ANTIBODIES].

Authors: S G NICOLAU; A BAEDAENOIU; M GAVRILESCU
Journal: Arch Klin Exp Dermatol Date: 1964-10-20

6. Adjuvant-antigen relationships in the production of experimental "allergic" encephalomyelitis in the guinea pig.

Authors: C M SHAW; E C ALVORD; W J FAHLBERG; M W KIES
Journal: J Exp Med Date: 1962-01-01 Impact factor: 14.307

7. [Skin hypersensitivity to purified myelin antigen in neurological diseases, with special reference to multiple sclerosis].

Authors: G PAAL; D BOEHME; H KERSTEN; W KERSTEN
Journal: Dtsch Z Nervenheilkd Date: 1963