Literature DB >> 19870253

THE FILTERING CAPACITY OF LYMPH NODES.

C K Drinker1, M E Field, H K Ward.   

Abstract

In anesthetized dogs the popliteal lymph node alone, and the popliteal and iliac lymph nodes in series, have been perfused with solutions containing dog erythrocytes and streptococci. The perfusions have been carried out under conditions of lymph flow and pressure within the limits of those occurring in the actively moving dog, or after a severe degree of inflammatory swelling has developed. Figures for filtration are given, with protocols of typical experiments. They indicate that normal lymph nodes possess a high degree of filtering efficiency-an efficiency so great as to make it fairly certain that in a part kept at rest early in an infection, practically no microorganisms would escape the nodes in the line of drainage.

Entities:  

Year:  1934        PMID: 19870253      PMCID: PMC2132334          DOI: 10.1084/jem.59.4.393

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  2 in total

1.  THE PROTEINS OF BLOOD AND SUBCUTANEOUS LYMPH IN DOGS.

Authors:  A A Weech; E Goettsch; E B Reeves
Journal:  J Clin Invest       Date:  1933-11       Impact factor: 14.808

2.  LYMPH PRESSURES IN STERILE INFLAMMATION.

Authors:  M E Field; C K Drinker; J C White
Journal:  J Exp Med       Date:  1932-08-31       Impact factor: 14.307

  2 in total
  17 in total

1.  Structure of sinuses in the human lymph node.

Authors:  P G Forkert; J A Thliveris; F D Bertalanffy
Journal:  Cell Tissue Res       Date:  1977-09-14       Impact factor: 5.249

2.  Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation.

Authors:  John C Kraft; Lisa A McConnachie; Josefin Koehn; Loren Kinman; Jianguo Sun; Ann C Collier; Carol Collins; Danny D Shen; Rodney J Y Ho
Journal:  J Control Release       Date:  2018-02-10       Impact factor: 9.776

Review 3.  Nanodrug formulations to enhance HIV drug exposure in lymphoid tissues and cells: clinical significance and potential impact on treatment and eradication of HIV/AIDS.

Authors:  Jingwei Shao; John C Kraft; Bowen Li; Jesse Yu; Jennifer Freeling; Josefin Koehn; Rodney Jy Ho
Journal:  Nanomedicine (Lond)       Date:  2016-02-19       Impact factor: 5.307

Review 4.  Stromal cell contributions to the homeostasis and functionality of the immune system.

Authors:  Scott N Mueller; Ronald N Germain
Journal:  Nat Rev Immunol       Date:  2009-07-31       Impact factor: 53.106

5.  Indocyanine green nanoparticles undergo selective lymphatic uptake, distribution and retention and enable detailed mapping of lymph vessels, nodes and abnormalities.

Authors:  John C Kraft; Piper M Treuting; Rodney J Y Ho
Journal:  J Drug Target       Date:  2018-02-12       Impact factor: 5.121

6.  THE FORMATION OF AGGLUTININS WITHIN LYMPH NODES.

Authors:  P D McMaster; S S Hudack
Journal:  J Exp Med       Date:  1935-05-31       Impact factor: 14.307

7.  Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex.

Authors:  J E Gretz; C C Norbury; A O Anderson; A E Proudfoot; S Shaw
Journal:  J Exp Med       Date:  2000-11-20       Impact factor: 14.307

8.  THE LYMPHATIC PATHWAY FROM THE NOSE AND PHARYNX : THE DISSEMINATION OF NASALLY INSTILLED VACCINIA VIRUS.

Authors:  J M Yoffey; E R Sullivan
Journal:  J Exp Med       Date:  1939-01-01       Impact factor: 14.307

9.  Cellular mechanisms of antibacterial defense in lymph nodes; pathogenesis of acute bacterial lymphadenitis.

Authors:  R O SMITH; W B WOOD
Journal:  J Exp Med       Date:  1949-12       Impact factor: 14.307

10.  STUDIES ON MALARIAL PARASITES : VII. METHODS AND TECHNIQUES FOR CULTIVATION.

Authors:  Q M Geiman; C B Anfinsen; R W McKee; R A Ormsbee; E G Ball
Journal:  J Exp Med       Date:  1946-11-30       Impact factor: 14.307

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