Literature DB >> 19870233

THE TOXIC PROPERTIES OF SERUM EXTRACTS OF HEMOLYTIC STREPTOCOCCI.

J T Weld1.   

Abstract

1. A method is described whereby toxic substances may be extracted from hemolytic streptococci with inactivated serum. 2. Such extracts contain large amounts of hemotoxin and leucocidin. 3. Their intravenous injection into mice causes marked hemoglobinuria, anemia, and death. 4. There is evidence that this anemia is not the only cause of death of these animals. 5. Incomplete work seems to indicate that the hemotoxin and the lethal poisons are not antigenic. 6. Certain biological properties of the extract are described.

Entities:  

Year:  1934        PMID: 19870233      PMCID: PMC2132339          DOI: 10.1084/jem.59.1.83

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  5 in total

1.  STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : IV. STREPTOLYSIN.

Authors:  J M Neill; T B Mallory
Journal:  J Exp Med       Date:  1926-07-31       Impact factor: 14.307

2.  ANTIGENIC STREPTOCOCCAL HEMOLYSIN.

Authors:  E W Todd
Journal:  J Exp Med       Date:  1932-01-31       Impact factor: 14.307

3.  THE CONVERSION OF HEMOLYTIC STREPTOCOCCI TO NON-HEMOLYTIC FORMS.

Authors:  E W Todd
Journal:  J Exp Med       Date:  1928-09-30       Impact factor: 14.307

4.  STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : IV. OXIDATION OF HEMOTOXIN IN STERILE EXTRACTS OF PNEUMOCOCCUS.

Authors:  O T Avery; J M Neill
Journal:  J Exp Med       Date:  1924-04-30       Impact factor: 14.307

5.  DIFFERENTIATION BETWEEN CERTAIN TOXIC PROPERTIES OF FILTRATES OF HEMOLYTIC STAPHYLOCOCCUS AUREUS.

Authors:  J T Weld; A Gunther
Journal:  J Exp Med       Date:  1931-07-31       Impact factor: 14.307

  5 in total
  7 in total

1.  Formation of a bacterial toxin (streptolysin S) by resting cells.

Authors:  A W BERNHEIMER
Journal:  J Exp Med       Date:  1949-11       Impact factor: 14.307

2.  Reduced virulence of group A streptococcal Tn916 mutants that do not produce streptolysin S.

Authors:  S D Betschel; S M Borgia; N L Barg; D E Low; J C De Azavedo
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441

Review 3.  Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Authors:  Paul G Arnison; Mervyn J Bibb; Gabriele Bierbaum; Albert A Bowers; Tim S Bugni; Grzegorz Bulaj; Julio A Camarero; Dominic J Campopiano; Gregory L Challis; Jon Clardy; Paul D Cotter; David J Craik; Michael Dawson; Elke Dittmann; Stefano Donadio; Pieter C Dorrestein; Karl-Dieter Entian; Michael A Fischbach; John S Garavelli; Ulf Göransson; Christian W Gruber; Daniel H Haft; Thomas K Hemscheidt; Christian Hertweck; Colin Hill; Alexander R Horswill; Marcel Jaspars; Wendy L Kelly; Judith P Klinman; Oscar P Kuipers; A James Link; Wen Liu; Mohamed A Marahiel; Douglas A Mitchell; Gert N Moll; Bradley S Moore; Rolf Müller; Satish K Nair; Ingolf F Nes; Gillian E Norris; Baldomero M Olivera; Hiroyasu Onaka; Mark L Patchett; Joern Piel; Martin J T Reaney; Sylvie Rebuffat; R Paul Ross; Hans-Georg Sahl; Eric W Schmidt; Michael E Selsted; Konstantin Severinov; Ben Shen; Kaarina Sivonen; Leif Smith; Torsten Stein; Roderich D Süssmuth; John R Tagg; Gong-Li Tang; Andrew W Truman; John C Vederas; Christopher T Walsh; Jonathan D Walton; Silke C Wenzel; Joanne M Willey; Wilfred A van der Donk
Journal:  Nat Prod Rep       Date:  2013-01       Impact factor: 13.423

4.  THE CELLULAR ANTIGENS OF GROUP A STREPTOCOCCI; IMMUNOELECTROPHORETIC STUDIES OF THE C, M, T, PGP, E4, F, AND E ANTIGENS OF SEROTYPE 17 STREPTOCOCCI.

Authors:  A T WILSON; G G WILEY
Journal:  J Exp Med       Date:  1963-10-01       Impact factor: 14.307

5.  The leukotoxic action of streptococci.

Authors:  A T WILSON
Journal:  J Exp Med       Date:  1957-05-01       Impact factor: 14.307

6.  OXYGEN-STABLE HEMOLYSINS OF GROUP A STREPTOCCI. IV. STUDIES ON THE MECHANISM OF LYSIS BY CELL-BOUND HEMOLYSIN OF RED BLOOD CELLS AND EHRLICH ASCITES TUMOR CELLS.

Authors:  I GINSBURG; T N HARRIS
Journal:  J Exp Med       Date:  1965-04-01       Impact factor: 14.307

7.  A STABLE HEMOLYSIN-LEUCOCIDIN AND ITS CRYSTAL-LINE DERIVATIVE ISOLATED FROM BETA HEMOLYTIC STREPTOCOCCI.

Authors:  E J Czarnetzky; I M Morgan; S Mudd
Journal:  J Exp Med       Date:  1938-03-31       Impact factor: 14.307

  7 in total

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