Literature DB >> 19869852

IMMUNIZATION WITH MIXTURES OF POLIOMYELITIS VIRUS AND ALUMINUM HYDROXIDE.

C P Rhoads1.   

Abstract

Preliminary experiments are presented which indicate that poliomyelitis virus can be inactivated by a certain preparation of aluminum hydroxide. This effect is seen at neutrality and at a pH of 5.5, but not at a pH of 8.8. Monkeys treated by repeated subcutaneous injections of poliomyelitis virus so inactivated evince immunity as shown by resistance to intranasal instillation and intracerebral inoculation as well as by the neutralizing power of their sera. The treatments which give rise to the immunity produce no symptoms of disease.

Entities:  

Year:  1931        PMID： 19869852      PMCID： PMC2131962          DOI： 10.1084/jem.53.3.399

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  1 in total

1.  SURVIVAL OF THE VIRUS OF POLIOMYELITIS FOR EIGHT YEARS IN GLYCEROL.

Authors:  C P Rhoads
Journal:  J Exp Med       Date:  1929-03-31       Impact factor: 14.307
  1 in total
  3 in total

1.  [On the use of aluminum hydroxide for purification and differentiation of enteroviruses. I. Studies on adsorption and elution of poliomyelitis viruses with the use of aluminum hydroxide as adsorbent].

Authors:  R HAAS; R THOMSSEN; G MAASS; A GIESELER
Journal:  Z Hyg Infektionskr       Date:  1961

2.  Studies on immunity in poliomyelitis. I. Homologous immunity produced with ultraviolet-irradiated adsorbate vaccine.

Authors:  J D VERLINDE; A KLARENBEEK
Journal:  Arch Gesamte Virusforsch       Date:  1952

3.  ACTIVE IMMUNICATION OF GUINEA PIGS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : I. QUANTITATIVE EXPERIMENTS WITH VARIOUS PREPARATIONS OF ACTIVE VIRUS.

Authors:  P K Olitsky; H R Cox
Journal:  J Exp Med       Date:  1936-02-29       Impact factor: 14.307
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.