| Literature DB >> 19869742 |
C L Derick1, C H Hitchcock, H F Swift.
Abstract
The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness-"allergy," "hyperergy"-against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a preliminary sensitizing period of about 2 weeks' duration with either large initial, or small multiple daily inoculations, the later foci need be produced only at 7 to 10 day intervals. Chronicity of low-grade infection appears to be an important factor in the attainment of a high degree of hypersensitiveness.Entities:
Year: 1930 PMID: 19869742 PMCID: PMC2131870 DOI: 10.1084/jem.52.1.1
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307