Literature DB >> 19868872

AN IMMUNIZING STRAIN OF THE VIRUS OF POLIOMYELITIS.

S Flexner1, H L Amoss.   

Abstract

In this communication we have described a strain of the virus of poliomyelitis derived from a rapidly fatal human case, which exhibits mild degrees of infective power and marked degrees of protective effect for the monkey. While Macacus rhesus displays perceptible differences in suceptibility to the attenuated virus, nearly all individuals respond to the inoculation and none succumbs to the infection induced. As compared with previously described examples of experimental poliomyelitis, the modified disease described in this paper is distinguished by its relatively benign nature and its tendency to end in recovery rather than, as with the earlier observed instances, in death.

Entities:  

Year:  1924        PMID: 19868872      PMCID: PMC2128531          DOI: 10.1084/jem.39.5.625

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  3 in total

1.  A CONTRIBUTION TO THE EPIDEMIOLOGY OF POLIOMYELITIS.

Authors:  S Flexner; P F Clark; H L Amoss
Journal:  J Exp Med       Date:  1914-02-01       Impact factor: 14.307

2.  EXPERIMENTAL EPIDEMIC POLIOMYELITIS IN MONKEYS.

Authors:  S Flexner; P A Lewis
Journal:  J Exp Med       Date:  1910-03-14       Impact factor: 14.307

3.  REVIVED ACTIVITY OF THE VIRUS OF POLIOMYELITIS.

Authors:  S Flexner; H L Amoss
Journal:  J Exp Med       Date:  1924-01-31       Impact factor: 14.307

  3 in total
  2 in total

1.  EXPERIMENTS ON ACTIVE IMMUNIZATION AGAINST EXPERIMENTAL POLIOMYELITIS.

Authors:  P K Olitsky; H R Cox
Journal:  J Exp Med       Date:  1936-01-01       Impact factor: 14.307

2.  VIRUSES OF POLIOMYELITIS : AN IMMUNOLOGICAL COMPARISON OF SIX STRAINS.

Authors:  J D Trask; J R Paul; A R Beebe; W J German
Journal:  J Exp Med       Date:  1937-04-30       Impact factor: 14.307

  2 in total

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