Literature DB >> 19868783

STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : IV. BACTERIOLYTIC ENZYME.

O T Avery1, G E Cullen.   

Abstract

1. Pneumococci possess an active intracellular enzyme which causes lysis of heat-killed pneumococci of the same and heterologous types and to a less degree of a closely related organism, Streptococcus viridans. 2. The optimum reaction for lysis lies between pH 6 and 8. 3. The bacteriolytic action is proportional to the concentration of the enzyme. 4. Heating the enzyme for 30 minutes at 60 degrees C. destroys its activity. 5. The possible relation of the enzyme to autolysis is discussed.

Entities:  

Year:  1923        PMID: 19868783      PMCID: PMC2128432          DOI: 10.1084/jem.38.2.199

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  1 in total

1.  STUDIES ON THE ENZYMES OF PNEUMOCOCCUS : I. PROTEOLYTIC ENZYMES.

Authors:  O T Avery; G E Cullen
Journal:  J Exp Med       Date:  1920-10-31       Impact factor: 14.307

  1 in total
  12 in total

1.  A novel protein, RafX, is important for common cell wall polysaccharide biosynthesis in Streptococcus pneumoniae: implications for bacterial virulence.

Authors:  Kaifeng Wu; Jian Huang; Yanqing Zhang; Wenchun Xu; Hongmei Xu; Libin Wang; Ju Cao; Xuemei Zhang; Yibing Yin
Journal:  J Bacteriol       Date:  2014-07-07       Impact factor: 3.490

Review 2.  Molecular control of bacterial death and lysis.

Authors:  Kelly C Rice; Kenneth W Bayles
Journal:  Microbiol Mol Biol Rev       Date:  2008-03       Impact factor: 11.056

3.  LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan.

Authors:  Peter Mellroth; Robert Daniels; Alice Eberhardt; Daniel Rönnlund; Hans Blom; Jerker Widengren; Staffan Normark; Birgitta Henriques-Normark
Journal:  J Biol Chem       Date:  2012-02-09       Impact factor: 5.157

4.  THE AUTOLYTIC SYSTEM OF PNEUMOCOCCI.

Authors:  R J Dubos
Journal:  J Exp Med       Date:  1937-05-31       Impact factor: 14.307

5.  THE EFFECT OF THE BACTERIOLYTIC ENZYME OF PNEUMOCOCCUS UPON THE ANTIGENICITY OF ENCAPSULATED PNEUMOCOCCI.

Authors:  R J Dubos
Journal:  J Exp Med       Date:  1937-06-30       Impact factor: 14.307

6.  THE PRODUCTION OF PURPURA BY DERIVATIVES OF PNEUMOCOCCUS : III. FURTHER STUDIES ON THE NATURE OF THE PURPURA-PRODUCING PRINCIPLE.

Authors:  L A Julianelle; H A Reimann
Journal:  J Exp Med       Date:  1927-03-31       Impact factor: 14.307

7.  THE HYDROLYSIS OF HYALURONIC ACID BY BACTERIAL ENZYMES.

Authors:  K Meyer; G L Hobby; E Chaffee; M H Dawson
Journal:  J Exp Med       Date:  1940-01-31       Impact factor: 14.307

8.  A STUDY OF PNEUMOCOCCUS AUTOLYSIS.

Authors:  W F Goebel; O T Avery
Journal:  J Exp Med       Date:  1929-01-31       Impact factor: 14.307

9.  THE PRODUCTION OF PURPURA BY DERIVATIVES OF PNEUMOCOCCUS : I. GENERAL CONSIDERATIONS OF THE REACTION.

Authors:  L A Julianelle; H A Reimann
Journal:  J Exp Med       Date:  1926-01-01       Impact factor: 14.307

10.  THE EFFECT OF FORMALDEHYDE ON PNEUMOCOCCI.

Authors:  R J Dubos
Journal:  J Exp Med       Date:  1938-02-28       Impact factor: 14.307

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