Literature DB >> 1986871

Identification of an autocrine negative growth factor: mouse beta-galactoside-binding protein is a cytostatic factor and cell growth regulator.

V Wells1, L Mallucci.   

Abstract

Murine beta-galactoside-binding protein, a protein classified as a soluble lectin, is shown to be a cell growth-regulatory molecule and a cytostatic factor. The growth-inhibitory effect is not related to lectin properties, and competition assays indicate that the protein binds to specific cell surface receptors with high affinity. It exerts control in G0 and at G2, both as a regulator of cell replication and as a cytostatic factor.

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Year:  1991        PMID： 1986871     DOI： 10.1016/0092-8674(91)90211-g

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  43 in total

1.  A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.

Authors:  Masanori Sakaguchi; Tetsuro Shingo; Takuya Shimazaki; Hirotaka James Okano; Mieko Shiwa; Satoru Ishibashi; Hideyuki Oguro; Mikiko Ninomiya; Toshihiko Kadoya; Hidenori Horie; Akira Shibuya; Hidehiro Mizusawa; Françoise Poirier; Hiromitsu Nakauchi; Kazunobu Sawamoto; Hideyuki Okano
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-24       Impact factor: 11.205

2.  Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells.

Authors:  Purevdorj B Olkhanud; Dolgor Baatar; Monica Bodogai; Fran Hakim; Ronald Gress; Robin L Anderson; Jie Deng; Mai Xu; Susanne Briest; Arya Biragyn
Journal:  Cancer Res       Date:  2009-06-30       Impact factor: 12.701

3.  Cell-specific transcriptional regulation and reactivation of galectin-1 gene expression are controlled by DNA methylation of the promoter region.

Authors:  G Benvenuto; M L Carpentieri; P Salvatore; L Cindolo; C B Bruni; L Chiariotti
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272

4.  Expression of the 14 kDa and 16 kDa galactoside-binding lectins during differentiation of the chick yolk sac.

Authors:  Christopher K Guay; Sara E Zalik
Journal:  Rouxs Arch Dev Biol       Date:  1994-12

5.  Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma.

Authors:  M M Lotz; C W Andrews; C A Korzelius; E C Lee; G D Steele; A Clarke; A M Mercurio
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

6.  Dissociation of the carbohydrate-binding and splicing activities of galectin-1.

Authors:  Patricia G Voss; Richard M Gray; Seth W Dickey; Weizhong Wang; Jung W Park; Ken-Ichi Kasai; Jun Hirabayashi; Ronald J Patterson; John L Wang
Journal:  Arch Biochem Biophys       Date:  2008-07-16       Impact factor: 4.013

7.  Energetics of carbohydrate binding by a 14 kDa S-type mammalian lectin.

Authors:  R Ramkumar; A Surolia; S K Podder
Journal:  Biochem J       Date:  1995-05-15       Impact factor: 3.857

8.  Structure of S-lectin, a developmentally regulated vertebrate beta-galactoside-binding protein.

Authors:  D I Liao; G Kapadia; H Ahmed; G R Vasta; O Herzberg
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

9.  Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle.

Authors:  Marcelo Dias-Baruffi; Sean R Stowell; Shuh-Chyung Song; Connie M Arthur; Moonjae Cho; Lilian C Rodrigues; Marlise A B Montes; Marcos A Rossi; Judith A James; Rodger P McEver; Richard D Cummings
Journal:  Glycobiology       Date:  2010-01-05       Impact factor: 4.313

10.  Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death.

Authors:  Valerie Wells; Livio Mallucci
Journal:  Breast Cancer Res       Date:  2009-01-08       Impact factor: 6.466
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