STUDIES ON X-RAY EFFECTS : VIII. INFLUENCE OF CANCER INOCULATION ON THE LYMPHOID STIMULATION INDUCED BY SMALL DOSES OF X-RAYS.

Mice treated with small doses of x-rays and inoculated with cancer immediately afterwards, show a marked suppression of lymphoid proliferation. If, however, the cancer inoculation is made 7 days after the exposure to x-rays, thus permitting the primary lymphoid stimulation known to occur soon after the x-ray treatment to arise, a second stimulation takes place in a large proportion of mice thus inoculated. Changes in the blood of mice x-rayed and inoculated with cancer 7 days afterwards show that the state of resistance to cancer inoculation is attended by blood lymphocytosis, as is the case in all other varieties of immunity to transplanted cancer so far studied.