DETERMINATION OF THE QUANTITY OF SECRETING TISSUE IN THE LIVING KIDNEY.

1. Under the strain induced by the administration of urea, it is possible to demonstrate the relation between the degree of anatomical damage in the kidney and the degree of defect in the urea-excreting capacity induced by uranium. 2. The closest correlation between structure and function was obtained when the ratio between the urea content of the urine and of the blood was used as the measure of function.