Literature DB >> 19867899

THE OCCURRENCE OF CARRIERS OF DISEASE-PRODUCING TYPES OF PNEUMOCOCCUS.

A R Dochez1, O T Avery.   

Abstract

Lobar pneumonia in 75 per cent of instances is due to specific types of pneumococci possessed of a high degree of pathogenicity. Although pneumococci occur in the mouths of 60 per cent of normal individuals, such organisms are readily distinguishable from the highly parasitic types of pneumococcus responsible for the severe forms of lobar pneumonia, a convincing proof that infection in this disease is, in the majority of instances, not autogenic in nature, but is derived from some extraneous source. In a high percentage of instances healthy persons intimately associated with cases of lobar pneumonia harbor the disease-producing types of pneumococcus. In every such instance the pneumococcus isolated has corresponded in type with that of the infected individual. Convalescents from pneumonia carry for a considerable length of time the type of pneumococcus with which they have been infected. The existence of the carrier state among healthy persons and among those recently recovered from pneumonia establishes a basis for understanding the mechanism by means of which lobar pneumonia spreads and maintains its high incidence from year to year.

Entities:  

Year:  1915        PMID: 19867899      PMCID: PMC2125302          DOI: 10.1084/jem.22.1.105

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  1 in total

1.  VARIETIES OF PNEUMOCOCCUS AND THEIR RELATION TO LOBAR PNEUMONIA.

Authors:  A R Dochez; O T Avery
Journal:  J Exp Med       Date:  1915-02-01       Impact factor: 14.307

  1 in total
  10 in total

1.  THE EPIDEMIOLOGY OF PNEUMOCOCCUS INFECTION : THE INCIDENCE AND SPREAD OF PNEUMOCOCCI IN THE NASAL PASSAGES AND THROATS OF HEALTHY PERSONS.

Authors:  L T Webster; T P Hughes
Journal:  J Exp Med       Date:  1931-03-31       Impact factor: 14.307

2.  STUDIES ON BACTERIAL NUTRITION : IV. EFFECT OF PLANT TISSUE UPON GROWTH OF PNEUMOCOCCUS AND STREPTOCOCCUS.

Authors:  H J Morgan; O T Avery
Journal:  J Exp Med       Date:  1923-07-31       Impact factor: 14.307

3.  INTRANASAL VIRULENCE OF PNEUMOCOCCI FOR MICE.

Authors:  L T Webster; A D Clow
Journal:  J Exp Med       Date:  1933-09-30       Impact factor: 14.307

4.  STUDIES ON MENINGOCOCCUS INFECTION : VII. THE STUDY OF AN ISOLATED EPIDEMIC.

Authors:  G Rake
Journal:  J Exp Med       Date:  1935-03-31       Impact factor: 14.307

5.  THE INTESTINAL FLORA IN MOUSE TYPHOID INFECTION.

Authors:  L T Webster
Journal:  J Exp Med       Date:  1923-01-01       Impact factor: 14.307

6.  A CONTRIBUTION TO THE EPIDEMIOLOGY OF LOBAR PNEUMONIA.

Authors:  E G Stillman
Journal:  J Exp Med       Date:  1916-12-01       Impact factor: 14.307

7.  EPIDEMIOLOGICAL STUDIES ON RESPIRATORY INFECTIONS OF THE RABBIT : VIII. CARRIERS OF BACTERIUM LEPISEPTICUM.

Authors:  L T Webster
Journal:  J Exp Med       Date:  1926-03-31       Impact factor: 14.307

8.  METHEMOGLOBIN FORMATION BY STERILE CULTURE FILTRATES OF PNEUMOCOCCUS.

Authors:  H J Morgan; J M Neill
Journal:  J Exp Med       Date:  1924-07-31       Impact factor: 14.307

9.  FURTHER STUDIES ON THE EPIDEMIOLOGY OF LOBAR PNEUMONIA.

Authors:  E G Stillman
Journal:  J Exp Med       Date:  1917-10-01       Impact factor: 14.307

10.  Dried Saliva Spots: A Robust Method for Detecting Streptococcus pneumoniae Carriage by PCR.

Authors:  Cassandra L Krone; Anna E Oja; Kirsten van de Groep; Elisabeth A M Sanders; Debby Bogaert; Krzysztof Trzciński
Journal:  Int J Mol Sci       Date:  2016-03-05       Impact factor: 5.923

  10 in total

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