Literature DB >> 1986788

Photometric or fluorometric assay of cathepsin B, L and H and papain using substrates with an aminotrifluoromethylcoumarin leaving group.

J R Tchoupe1, T Moreau, F Gauthier, J G Bieth.   

Abstract

N-trifluoromethylcoumarinylamide derivatives of benzyloxycarbonyl-Arg-Arg, benzyloxycarbonyl-Phe-Arg and Arg are convenient chromogenic and fluorogenic substrates of cathepsin B, L and H, respectively. Benzyloxycarbonyl-Phe-Arg-N-trifluoromethylcoumarinylamide is also a highly sensitive substrate for papain.

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Year:  1991        PMID： 1986788     DOI： 10.1016/0167-4838(91)90232-o

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  19 in total

1.  Recombinant silicateins as model biocatalysts in organosiloxane chemistry.

Authors:  S Yasin Tabatabaei Dakhili; Stephanie A Caslin; Abayomi S Faponle; Peter Quayle; Sam P de Visser; Lu Shin Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-19       Impact factor: 11.205

2.  Inactivation of papain by antithrombin due to autolytic digestion: a model of serpin inactivation of cysteine proteinases.

Authors:  I Björk; K Nordling; E Raub-Segall; U Hellman; S T Olson
Journal:  Biochem J       Date:  1998-11-01       Impact factor: 3.857

3.  Effects of Ghrelin on the Proteolytic Pathways of Alzheimer's Disease Neuronal Cells.

Authors:  Valentina Cecarini; Laura Bonfili; Massimiliano Cuccioloni; Jeffrey N Keller; Annadora J Bruce-Keller; Anna Maria Eleuteri
Journal:  Mol Neurobiol       Date:  2015-06-02       Impact factor: 5.590

4.  Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases.

Authors:  G Lalmanach; C Serveau; M Brillard-Bourdet; J R Chagas; R Mayer; L Juliano; F Gauthier
Journal:  J Protein Chem       Date:  1995-11

5.  Purification and characterization of a new cystatin inhibitor from Taiwan cobra (Naja naja atra) venom.

Authors:  M Brillard-Bourdet; V Nguyên; M Ferrer-di Martino; F Gauthier; T Moreau
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

6.  MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity.

Authors:  Wu Yang; John Guastella; Jin-Cheng Huang; Yan Wang; Li Zhang; Dong Xue; Minhtam Tran; Richard Woodward; Shailaja Kasibhatla; Ben Tseng; John Drewe; Sui Xiong Cai
Journal:  Br J Pharmacol       Date:  2003-08-26       Impact factor: 8.739

7.  Probing cathepsin K activity with a selective substrate spanning its active site.

Authors:  Fabien Lecaille; Enrico Weidauer; Maria A Juliano; Dieter Brömme; Gilles Lalmanach
Journal:  Biochem J       Date:  2003-10-15       Impact factor: 3.857

8.  Differences in cysteine protease activity in Schistosoma mansoni-resistant and -susceptible Biomphalaria glabrata and characterization of the hepatopancreas cathepsin B Full-length cDNA.

Authors:  Jocelyn Myers; Wannaporn Ittiprasert; Nithya Raghavan; André Miller; Matty Knight
Journal:  J Parasitol       Date:  2008-06       Impact factor: 1.276

9.  Tailoring the specificity of a plant cystatin toward herbivorous insect digestive cysteine proteases by single mutations at positively selected amino acid sites.

Authors:  Marie-Claire Goulet; Cindy Dallaire; Louis-Philippe Vaillancourt; Moustafa Khalf; Amine M Badri; Andreja Preradov; Marc-Olivier Duceppe; Charles Goulet; Conrad Cloutier; Dominique Michaud
Journal:  Plant Physiol       Date:  2008-01-11       Impact factor: 8.340

10.  Giardia duodenalis cathepsin B proteases degrade intestinal epithelial interleukin-8 and attenuate interleukin-8-induced neutrophil chemotaxis.

Authors:  James A Cotton; Amol Bhargava; Jose G Ferraz; Robin M Yates; Paul L Beck; Andre G Buret
Journal:  Infect Immun       Date:  2014-04-14       Impact factor: 3.441
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