BACKGROUND/ PURPOSE: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. METHODS: A review of the literature and authors experience was undertaken. RESULTS: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. CONCLUSIONS: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.
BACKGROUND/ PURPOSE: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. METHODS: A review of the literature and authors experience was undertaken. RESULTS: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. CONCLUSIONS: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.
Authors: Jasper Jan Atema; Anneke P J Jilesen; Olivier R C Busch; Thomas M van Gulik; Dirk J Gouma; Els J M Nieveen van Dijkum Journal: HPB (Oxford) Date: 2014-07-18 Impact factor: 3.647
Authors: Lapo Bencini; Mario Annecchiarico; Marco Farsi; Ilenia Bartolini; Vita Mirasolo; Francesco Guerra; Andrea Coratti Journal: World J Gastrointest Oncol Date: 2015-12-15