| Literature DB >> 19863701 |
Gaetano Magro1, Michal Michal, Rita Alaggio, Emanuele D'Amore.
Abstract
Proliferative fasciitis (PF) is a pseudosarcomatous proliferation which typically occurs in the subcutaneous tissue and fascia. Although patients are characteristically middle-aged people, occasionally PF can arise in children. Histologically, PF is characterized by a proliferation of large ganglion-like and spindle-shaped cells which, especially in childhood, may exhibit high mitotic activity, but no atypical mitoses. We report a case of PF in the dermis of a 13-year-old boy. This is the first case of PF primarily arising in the dermis. Apart from the unusual site, another intriguing finding was the presence of rare atypical mitoses, a feature which has not been previously emphasized in PF. Awareness that PF may occur in the dermis, exhibiting occasional atypical mitoses, is crucial to avoid a misdiagnosis of malignancy.Entities:
Mesh:
Year: 2011 PMID: 19863701 DOI: 10.1111/j.1600-0560.2009.01460.x
Source DB: PubMed Journal: J Cutan Pathol ISSN: 0303-6987 Impact factor: 1.587