Literature DB >> 19863701

Intradermal proliferative fasciitis in childhood: a potential diagnostic pitfall.

Gaetano Magro1, Michal Michal, Rita Alaggio, Emanuele D'Amore.   

Abstract

Proliferative fasciitis (PF) is a pseudosarcomatous proliferation which typically occurs in the subcutaneous tissue and fascia. Although patients are characteristically middle-aged people, occasionally PF can arise in children. Histologically, PF is characterized by a proliferation of large ganglion-like and spindle-shaped cells which, especially in childhood, may exhibit high mitotic activity, but no atypical mitoses. We report a case of PF in the dermis of a 13-year-old boy. This is the first case of PF primarily arising in the dermis. Apart from the unusual site, another intriguing finding was the presence of rare atypical mitoses, a feature which has not been previously emphasized in PF. Awareness that PF may occur in the dermis, exhibiting occasional atypical mitoses, is crucial to avoid a misdiagnosis of malignancy.
Copyright © 2009 John Wiley & Sons A/S.

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Year:  2011        PMID: 19863701     DOI: 10.1111/j.1600-0560.2009.01460.x

Source DB:  PubMed          Journal:  J Cutan Pathol        ISSN: 0303-6987            Impact factor:   1.587


  3 in total

1.  Misses and near misses in diagnosing nodular fasciitis and morphologically related reactive myofibroblastic proliferations: experience of a referral center with emphasis on frequency of USP6 gene rearrangements.

Authors:  Ramona Erber; Abbas Agaimy
Journal:  Virchows Arch       Date:  2018-04-05       Impact factor: 4.064

2.  Proliferative Fasciitis in Childhood: A Review of Clinical Data Apropos of a Case.

Authors:  Dimitrios Sfoungaris; Vassilios Mouravas; Chrysostomos Kepertis; Vassilios Lambropoulos; Ioannis Spyridakis
Journal:  J Clin Diagn Res       Date:  2017-02-01

3.  Intradermal Proliferative Fasciitis Occurring With Chondrodermatitis Nodularis Helicis.

Authors:  Ashley Elsensohn; Sasha Getty; Jessica Shiu; Sébastien de Feraudy
Journal:  Am J Dermatopathol       Date:  2018-02       Impact factor: 1.533

  3 in total

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