| Literature DB >> 1986257 |
K G Jensen1, O Andersen, M Rønne.
Abstract
In vitro exposure of PHA-stimulated human lymphocytes to organotin compounds resulted in statistically significant increases in the frequencies of hyperdiploid cells. When taken together with our previous study demonstrating spindle inhibiting effects of the same organotin compounds by an indirect method (Jensen et al., 1989), the present study strongly indicates that organotin compounds are able to induce aneuploidy, probably by affecting spindle function.Entities:
Mesh：
Substances：
Year: 1991 PMID： 1986257 DOI： 10.1016/0027-5107(91)90112-2
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433