Literature DB >> 19861402

Education reduces the effects of genetic susceptibilities to poor physical health.

Wendy Johnson1, Kirsten Ohm Kyvik, Erik L Mortensen, Axel Skytthe, G David Batty, Ian J Deary.   

Abstract

BACKGROUND: Greater education is associated with better physical health. This has been of great concern to public health officials. Most demonstrations show that education influences mean levels of health. Little is known about the influence of education on variance in health status, or about how this influence may impact the underlying genetic and environmental sources of health problems. This study explored these influences.
METHODS: In a 2002 postal questionnaire, 21 522 members of same-sex pairs in the Danish Twin Registry born between 1931 and 1982 reported physical health in the 12-item Short Form Health Survey. We used quantitative genetic models to examine how genetic and environmental variance in physical health differed with level of education, adjusting for birth-year effects.
RESULTS: and Conclusions As expected, greater education was associated with better physical health. Greater education was also associated with smaller variance in health status. In both sexes, 2 standard deviations (SDs) above mean educational level, variance in physical health was only about half that among those 2 SDs below. This was because fewer highly educated people reported poor health. There was less total variance in health primarily because there was less genetic variance. Education apparently reduced expression of genetic susceptibilities to poor health. The patterns of genetic and environmental correlations suggested that this might take place because more educated people manage their environments to protect their health. If so, fostering the personal charactieristics associated with educational attainment could be important in reducing the education-health gradient.

Entities:  

Mesh:

Year:  2009        PMID: 19861402     DOI: 10.1093/ije/dyp314

Source DB:  PubMed          Journal:  Int J Epidemiol        ISSN: 0300-5771            Impact factor:   7.196


  20 in total

1.  Detecting specific genotype by environment interactions using marginal maximum likelihood estimation in the classical twin design.

Authors:  Dylan Molenaar; Sophie van der Sluis; Dorret I Boomsma; Conor V Dolan
Journal:  Behav Genet       Date:  2011-12-07       Impact factor: 2.805

2.  Education, genetic ancestry, and blood pressure in African Americans and Whites.

Authors:  Amy L Non; Clarence C Gravlee; Connie J Mulligan
Journal:  Am J Public Health       Date:  2012-06-14       Impact factor: 9.308

3.  Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population.

Authors:  D Corella; P Carrasco; J V Sorlí; O Coltell; C Ortega-Azorín; M Guillén; J I González; C Sáiz; R Estruch; J M Ordovas
Journal:  Nutr Metab Cardiovasc Dis       Date:  2010-12-24       Impact factor: 4.222

4.  Biological pathways and genetic mechanisms involved in social functioning.

Authors:  Juan R Ordoñana; Meike Bartels; Dorret I Boomsma; David Cella; Miriam Mosing; Joao R Oliveira; Donald L Patrick; Ruut Veenhoven; Gert G Wagner; Mirjam A G Sprangers
Journal:  Qual Life Res       Date:  2012-10-10       Impact factor: 4.147

5.  A note on false positives and power in G × E modelling of twin data.

Authors:  Sophie van der Sluis; Danielle Posthuma; Conor V Dolan
Journal:  Behav Genet       Date:  2011-07-07       Impact factor: 2.805

6.  Does the FTO gene interact with the socioeconomic status on the obesity development among young European children? Results from the IDEFICS study.

Authors:  R Foraita; F Günther; W Gwozdz; L A Reisch; P Russo; F Lauria; A Siani; T Veidebaum; M Tornaritis; L Iacoviello; K Vyncke; Y Pitsiladis; S Mårild; D Molnár; L A Moreno; K Bammann; I Pigeot
Journal:  Int J Obes (Lond)       Date:  2014-08-19       Impact factor: 5.095

Review 7.  Socioeconomic status and the health of youth: a multilevel, multidomain approach to conceptualizing pathways.

Authors:  Hannah M C Schreier; Edith Chen
Journal:  Psychol Bull       Date:  2012-07-30       Impact factor: 17.737

Review 8.  Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world.

Authors:  Scott I Vrieze; William G Iacono; Matt McGue
Journal:  Dev Psychopathol       Date:  2012-11

9.  Education and alcohol use: A study of gene-environment interaction in young adulthood.

Authors:  Peter B Barr; Jessica E Salvatore; Hermine Maes; Fazil Aliev; Antti Latvala; Richard Viken; Richard J Rose; Jaakko Kaprio; Danielle M Dick
Journal:  Soc Sci Med       Date:  2016-06-22       Impact factor: 4.634

10.  Pathways from childhood abuse and other adversities to adult health risks: The role of adult socioeconomic conditions.

Authors:  Sarah A Font; Kathryn Maguire-Jack
Journal:  Child Abuse Negl       Date:  2015-06-06
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